摘要
宫腔粘连(intrauterine adhesions,IUA)是一种常见的子宫内膜损伤性疾病。随着频繁的宫腔操作及宫腔镜手术的普及,IUA的发病率和检出率逐年升高,已成为女性继发不孕的第二大病因。目前针对IUA的治疗,轻中度患者通过传统治疗方法尚能取得一定疗效,但对于重度或广泛内膜损伤的患者,子宫内膜再生和功能恢复已成为妇产科医生临床上棘手的问题。随着干细胞在再生医学领域的广泛研究,国内外学者相继证实子宫内膜干细胞的存在,为IUA的治疗提供了新思路。综述干细胞在IUA治疗中的研究进展。
Intrauterine adhesion （IUA） is a common gynecological disease which is associated with endometrial lesion. In recent years,with the popularity of uterine cavity operation and hysteroscopy surgery,the incidence of IUA,as well as the detection rate,is increasing year by year,which has become the second largest cause of secondary infertility in women. For the treatment of IUA,mild-to-moderate of it can obtain certain therapeutic effect with traditional treatment,but for severe or widespread lining damage,the endometrial regeneration and functional recovery have become intractable clinical problems. With extensive research in the field of stem cells in regenerative medicine ,domestic and foreign scholars have confirmed the presence of endometrial stem cells,which provides a new way for the treatment of IUA. In this paper,we make a review for the progress of stem cells in treatment of intrauterine adhesion.
出处
《国际妇产科学杂志》
CAS
2014年第6期632-635,共4页
Journal of International Obstetrics and Gynecology
关键词
子宫内膜
干细胞
骨髓祖代细胞
宫腔粘连
Endometrium
Stem cells
Myeloid progenitor cells
Intrauterine adhesions
