摘要
【目的】观察清咽合剂治疗阴虚肺燥型喉源性咳嗽患者的临床疗效。【方法】选取符合纳入标准的阴虚肺燥型喉源性咳嗽患者60例,随机分为治疗组和对照组各30例。治疗组给予口服清咽合剂治疗,对照组给予酮替芬+咳必清治疗,2组疗程均为10 d。观察2组的整体疗效和临床症状、体征疗效。【结果】(1)临床整体疗效:治疗组治愈6例,显效14例,有效8例,总有效率为93.3%;对照组治愈1例,显效7例,有效17例,总有效率为83.3%。治疗组的临床整体疗效明显优于对照组(P<0.01)。(2)临床单个症状、体征疗效:在干咳方面,治疗组的疗效明显优于对照组(P<0.01);而在咽干、咽痒、咽部异物感、咽部体征方面,2组比较差异均无统计学意义(P>0.05)。(3)临床主要症状总积分:治疗2个疗程后,2组各临床主要症状总积分均明显降低,与治疗前比较差异均有统计学意义(P<0.05或P<0.01)。【结论】采用清咽合剂治疗阴虚肺燥型喉源性咳嗽,能明显改善患者的临床症状和体征。
Objective To investigate the therapeutic effect of Qingyan Mixture for laryngeal cough patients with lung dryness due to yin deficiency. Methods Sixty laryngeal cough patients with lung dryness due to yin deficiency were evenly randomized into treatment group and control group. The treatment group was given oral use of Qingyan Mixture, and the control group was given oral use of Ketotifen and Carbetapentane. The course of treatment for both groups lasted for 10 days. The overall therapeutic effect, and the effect on individual symptom or sign were evaluated after treatment. Results （ 1） In the treatment group, six patients were cured, 14 were markedly effective, 8 were improved, 2 were ineffective and the total effective rate was 93.3%. In the control group, one case was cured, 7 were markedly effective, 17 were improved, 5 were ineffective and the total effective rate was 83.3%. The overall clinical effect in the treatment group was significantly higher than that in the control group （P〈0.01） . （2） As for the effect on individual symptom or sign, the treatment group showed stronger effect on dry cough than the control group （ P〈0.01） , while differences of dry pharynx, throat itching, foreign body sensation in the throat, and pharyngeal signs were insignificant between the two groups （P〉0.05） . （3） After treatment, the total scores of main symptoms were decreased in both groups （P〈0.05 or P〈0.01） compared with those before treatment. Conclusion Qingyan Mixture shows certain effect on relieving symptoms and signs of laryngeal cough patients with lung dryness due to yin deficiency.
出处
《广州中医药大学学报》
CAS
北大核心
2014年第6期880-884,共5页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
清咽合剂
喉源性咳嗽/中药疗法
阴虚肺燥
养阴润肺
利咽止咳
Qingyan Mixture
Laryngeal cough/TCD therapy
Lung dryness due to yin deficiency
Nourishing yin to moisten lung
Relieving sore throat to arrest cough
