摘要
目的探讨慢性肾脏病(CKD)5期非透析患者血清镁浓度与冠状动脉粥样硬化性心脏病(CHD)及左心室功能的相关性。方法 43例CKD5期非透析患者根据是否患有CHD分为CHD组(24例)和对照组(19例),录入患者一般资料、血清镁、心率(HR)、每搏输出量(SV)、心搏指数(SI)、心输出量(CO)、心脏指数(CI)、射血前时间(PEP)、左心室射血时间(LVET)和PEP/LVET值。利用SPSS 15.0软件进行成组设计t检验及Pearson相关性分析。结果与对照组相比,CHD组患者血清镁水平、SV、SI及LVET偏低(P<0.05)。CHD组患者血清镁浓度与LVET呈正相关(r=0.66,P<0.01),与PEP/LVET值呈负相关(r=-0.38,P<0.05)。结论 CKD 5期非透析合并CHD患者的血清镁浓度偏低,且与左心室收缩功能相关。
Objective To investigate the correlation of serum magnesium level and coronary atherosclerotic heart disease （CHD） and left ventricular function of stage 5 patients with non-dialysis chronic kidney disease （CKD）. Methods According to the history of CHD, 43 stage 5 patients with non-dialysis CKD were divided into the GHD group （n =24） and control group （n =19）. Basic information, serum magnesium, heart rate （ HR）, stroke volume （ SV）, stroke index （ SI）, cardiac output （ CO）, cardiac index （ CI）, pre-ejection period （PEP）, left ventricular ejection time （LVET）, and PEP/LVET of patients were recorded. The t test and Pearson correlation analysis were conducted by the SPSS 15.0. Results The serum magnesium level, SV, SI, and LVET of the CHD group were lower than those of the control group （P〈0.05）. The serum magnesium level of the CHD group positively correlated to LVET （r=0.66, P〈0.01） and negatively correlated to PEP/ LVET （ r = -0.38, P〈0.05）. Conclusion The serum magnesium level of stage 5 patients with non-dialysis CKD and CHD was low and relevant to the left ventricular systolic function.
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2014年第11期1614-1617,共4页
Journal of Shanghai Jiao tong University:Medical Science
关键词
慢性肾脏病
血清镁
冠状动脉粥样硬化性心脏病
左心室功能
chronic kidney disease
serum magnesium
coronary atherosclerotic heart disease
left ventricular function
