摘要
本文采用三维有限元方法评价不同球-窝曲率半径的ProDisc人工颈椎间盘在植入颈椎后的生物力学差异,为人工椎间盘的设计改进和临床应用提供生物力学参考依据。首先建立C5-C6节段的三维有限元模型并验证,同时建立曲率半径分别为4、5和6mm的人工颈椎间盘有限元模型并分别植入C5-C6节段,对所有置换模型都施加74N的轴向压缩预载荷和1.8Nm的前屈/后伸、左右侧弯和轴向旋转力矩,进行有限元计算。计算结果显示球窝结构的曲率半径会改变植入节段的屈伸关节活动度,而在其他载荷下差异不明显。增大曲率半径可改善聚乙烯内衬应力集中现象,但同时也会伴随小关节力、韧带张力增大的不良结果。因此,人工椎间盘的设计应综合考虑保留运动节段的关节活动度同时又不致小关节、韧带、聚乙烯等的应力过大,以免影响长期临床效果。
This study was aimed to estimate the effect of different ProDisc-C arthroplasty designs after it was implan- ted to C5-C6 cervicalspine. Finite element （FE） model of intact C5-C6 segments including the vertebrae and disc was developed and validated. Ball-and-socket artificial disc prosthesis model （ProDisc-C, Synthes） was implanted into the validated FE model and the curvature of the ProDisc-C prosthesis was varied. All models were loaded with com- pressed force 74 N and the pure moment of 1.8 Nm along flexion-extension and bilateral bending and axial torsion separately. The results indicated that the variation in the curvature of ball and socket configuration would influence the range of motion in flexion/extension, while there were not apparently differences under other conditions of loads. The method increasing the curvature will solve the stress concentration of the polyethylene, but it will also bring ad- verse outcomes, such as facet joint force increasing and ligament tension increasing. Therefore, the design of artifi- cial discs should be considered comprehensively to reserve the range of motion as well as to avoid the adverse prob- lems, so as not to affect the long-term clinical results.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2014年第6期1265-1271,共7页
Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(11120101001
11202017
11421202)
教育部博士点基金资助项目(20121102120039
2013110213004)
国家科技支撑计划资助项目(2012BAI18B05
2012BAI18B07)
