摘要
本试验旨在研究饲粮添加黄芪多糖对大肠杆菌（ O55∶B5）脂多糖诱导的肉鸡免疫应激状态下蛋白质重分配的调节作用。试验采用2×2双因素设计将1日龄爱拔益加肉鸡144只随机分为4组，每组6个重复，每个重复6只鸡。2个试验因素分别为：免疫应激（注射生理盐水或脂多糖）和饲粮黄芪多糖（0或3 g/kg）。21-35日龄进行蛋白质沉积试验。结果显示，免疫应激显著降低了肉鸡平均日采食量、平均日增重、左侧胸肌的蛋白质沉积量及沉积率（ P〈0.05），同时显著提高了脾脏指数、脾脏蛋白质沉积量和脾脏、法氏囊的蛋白质沉积率（ P〈0.05）。而饲粮添加黄芪多糖可使肉鸡在免疫应激时，平均日采食量和平均日增重分别提高16.30%和18.34%，左侧胸肌的蛋白质沉积量和沉积率分别提高30.36%和12.34%，且显著抑制了脾脏蛋白质沉积量和沉积率的上升（ P〈0.05）。综上所述，在肉鸡免疫应激状态下，饲粮中添加3 g/kg黄芪多糖可抑制蛋白质从骨骼肌向免疫系统重分配，缓解肉鸡生长抑制。
This study was conducted to investigate the effects of Astragalus polysaccharide （ APS） on protein reallocation in broilers after challenge with E. coli （ O55∶B5） lipopolysaccharide （ LPS） . A total of 144 one-day-old Arbor Acres broilers were randomly divided into four groups （ six replicates per group and six birds per replicate） in terms of a 2×2 factorial design. The main factors were immune stress （ LPS or saline injection） and dietary APS （ 0 or 3 g/kg） . A trial of protein deposition was performed from 21 to 35 days of age. The re-sults showed that immune stress significantly reduced average daily feed intake （ ADFI ） , average daily gain （ ADG） , protein deposition （ PD） and protein deposition rate （ PDR） of the left pectoralis （ P〈0.05） . Mean-while, the spleen index, spleen PD, spleen and bursa of fabricius PDRs were significantly increased by im-mune stress （ P〈0. 05 ） . Under immune stress, however, ADFI and ADG were increased by 16. 30% and 18.34% respectively via dietary APS supplementation. The left pectoralis PD and PDR were increased by 30.36% and 12.34% respectively as well. The elevated spleen PD and PDR caused by immune stress were sig-nificantly decreased by dietary APS supplementation （P〈0.05）. In conclusion, dietary supplementation with 3 g/kg APS can inhibit protein redistribution from skeletal muscle to the immune system, and attenuate growth inhibition caused by immune stress.
出处
《动物营养学报》
CAS
CSCD
北大核心
2014年第12期3799-3805,共7页
CHINESE JOURNAL OF ANIMAL NUTRITION
基金
国家自然科学基金项目(31272464
31001017)
教育部新世纪优秀人才支持计划(NCET-12-0476)
留学人员科技活动择优资助项目(2012YX-02)
关键词
黄芪多糖
免疫应激
肉鸡
蛋白质沉积
生产性能
Astragalus polysaccharide
immune stress
broiler
protein deposition
performance
