摘要
目的 针对2013年我国赴中东朝觐归国人员集中开展呼吸道传染病抽样监测研究,重点监测中东呼吸综合征（MERS）及流感等呼吸道传染病感染情况。方法 从新疆、甘肃、北京等口岸共收集511份朝觐归国人员呼吸道样本,通过世界卫生组织（WHO）推荐的荧光定量RT-PCR方法检测中东呼吸综合征病毒,同时针对RNA样本开展甲型流感病毒、乙型流感病毒、偏肺病毒、呼吸道合胞病毒进行平行对照检测。结果 所有样本均未检出中东呼吸综合征病毒,其他4种病原核酸样本共检出阳性30份,其中甲型流感病毒20份,乙型流感病毒7份,偏肺病毒2份,呼吸道合胞病毒1份,总检出率为5.87%,甲流病毒检测率最高,为3.91%。女性朝觐人员呼吸道传染病病毒检出率为8.29%,高于男性的4.81%,所有感染者均在51-70岁之间。结论 2013年归国朝觐人员大样本抽查未检出MERS病毒感染,甲型流感病毒为朝觐人员中主要呼吸道感染病原体,其中女性和老年群体可能更易感染。
Objective This study was on the surveillance of respiratory infectious disease of Hajj pilgrims returning from Mecca in October 2013. The study was focused on the MERS virus and other respiratory viruses. Methods A total of 511 respiratory tract samples were collected from Xinjiang, Gansu and Beijing ports, and the detection of MERS virus was followed by WHO recommended RT-PCR method. Moreover, the influenza virus A,B, metapneumovirus and respiratory syncytial virus were detected as a parallel control. Results No MERS virus was detected in collected samples. Other respiratory infectious disease viruses were detected in 30 samples （influenza virus A 20 cases, influenza virus B 7 cases, metapneumovirus 2 cases and respiratory syncytial virus 1 case）. The total disease detection rate was 5.87%. The influenza virus A was the most frequent respiratory virus （3.91%）. Further demographic data analysis showed that female detection rate （8.29%） of respiratory virus was higher than the male （4.81%）, and all infected patients were in the range of 51-70 years old. Conclusion The MERS virus was not detected in Hajj pilgrims returning from Mecca this year. The influenza virus A was likely the most frequent pathogen of respiratory virus infection during pilgrimage. Furthermore, female and senior pilgrims may be more susceptible to infect the MERS virus during the Hajj.
出处
《中国国境卫生检疫杂志》
CAS
2014年第5期306-309,共4页
Chinese Journal of Frontier Health and Quarantine
基金
国家传染病重大科技专项(2013ZX10004101-006
2013ZX10004202-001-006)
关键词
中东呼吸综合征
呼吸道感染
朝觐
病毒感染
流感
Middle Eeast Respiratory Syndrome （MERS）
Respiratory tract infections
Pilgrimage
Virus infections
Influenza
