摘要
艾滋病病毒(HIV)和丙型肝炎病毒(HCV)的混合感染相当常见,两者混合感染后,疾病的进程、预后及治疗较单纯感染者均发生显著改变。近年来,有不少研究致力于混合感染者的发病机制,其中,细胞凋亡为一个重要的部分。文章就HIV、HCV单纯感染者和HIV/HCV混合感染者的肝细胞、免疫细胞的凋亡机制进行综述。
Objective Hepatitis C virus（HCV） co-infection is very common in human immunodeficiency virus （HIV） infected individuals. Disease progression, prognosis and therapy in coinfected patients are very different from those of single virus infected individuals. There have been many researches about the pathogenesis of coinfected indi- viduals in recent years, among which cell apoptosis is an important part. This review focuses on the apoptosis mech- anism of hepatocyte and immune cells in single infected and coinfected individuals.
出处
《中国艾滋病性病》
CAS
2014年第11期882-884,F0003,共4页
Chinese Journal of Aids & STD
基金
十二五重大专项(2012ZX10005010-001):中医药防治艾滋病临床科研基地建设~~
