摘要
目的探讨先天性心脏病患儿术后在ICU发生医院感染的临床特征及预防措施,以期减少医院感染的发生率。方法收集2011年1月-2012年12月ICU先天性心脏病术后监护的378例患儿,观察其术后医院感染的发生率、病原菌的分布与医院感染因素进行相关性分析,采用SPSS17.0进行统计分析。结果 21例患儿发生医院感染,感染率为5.56%;共检出细菌31株,主要为洋葱伯克霍尔德菌与大肠埃希菌,均占16.13%;单因素分析结果显示,患儿年龄、入住ICU天数、手术持续时间、输血量、呼吸机使用时间、胸腔引流时间、导尿管留置时间是发生医院感染的相关危险因素;多因素logistic回归分析结果表明,入住ICU时间、手术持续时间、输血量、呼吸机使用时间、胸腔引流时间、导尿管留置时间是发生医院感染重要的危险因素。结论加强医院感染管理,针对术后感染的危险因素,采取相应的预防与控制措施,可减少医院感染的发生。
OBJECTIVE To study the clinical features for postoperative nosocomial infections in the children with congenital heart disease who underwent cardiac surgery in ICU ,and to take corresponding prevention so as to de‐crease the incidence rate of nosocomial infections .METHODS A total of 378 children with congenital heart disease who underwent cardiac surgery were enrolled from Jan .2011 to Dec .2012 in ICU .The postoperative nosocomial infection rates ,pathogen distributions and risk factors were correlatively analyzed .SPSS 17 .0 was adopted for a statistic analysis .RESULTS The incidence rate of nosocomial infections in the children with congenital heart dis‐ease undergoing cardiac surgery was 5 .56% （21/378） .Totally 31 strains of bacteria were isolated ,among which mainly were Burkholderiacepacia and Escherichiacoli strains ,equally accounting for 16 .13% .The univariate a‐nalysis showed that the related risk factors of postoperative nosocomial infections was correlated with the age , length of ICU stay ,operation duration ,blood transfusion ,mechanical ventilation duration ,chest drainage time and catheterization duration .The multivariate logistic regression analysis indicated that the length of ICU stay , operation duration ,blood transfusion ,mechanical ventilation duration ,chest drainage time and catheterization du‐ration were the significant risk factors for the postoperative nosocomial infections .CONCLUSION The hospital should take the corresponding prevention and control measures targeted to the related risk factors so as to reduce the incidence of nosocomial infections .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第23期5948-5950,共3页
Chinese Journal of Nosocomiology
基金
国家自然科学基金资助项目(81270132)
关键词
先天性心脏病
医院感染
因素分析
预防措施
Congenital heart disease
Nosocomial infections
Factor analysis
Preventive measure
