摘要
发展了非血红素类四氮配体的铜配合物和2,2,6,6-四甲基哌啶-氮-氧自由基(TEMPO)相结合的催化体系,应用于分子氧参与的伯醇氧化反应.该体系具有条件温和、高效、高选择性、无需任何助剂和底物(包括苄醇、烯丙基醇和含杂原子伯醇)使用性强等优点.此外,利用高分辨质谱和紫外-光谱等对反应活性中间体进行了初步探讨.
A new system consisting of a copper（I） complex generated in situ from a tetradentate nitrogen lig-and and CuI in combination with 2,2,6,6-tetramethylpiperidine-1-oxyl （TEMPO） derivatives was successfully developed. The system was suitable for efficient and selective aerobic oxidation of primary benzyl and allyl alcohols with a wide range of functional groups to the corresponding al-dehydes at room temperature. The best result was obtained with N,N＇-dimethyl-N,N＇-bis（2-pyri-dylmethyl）ethane-1,2-diamine as the ligand and 4-OH-TEMPO as a cocatalyst in CH3CN. In addition, high-resolution mass spectrometry, ultraviolet-visible spectroscopy, and electrochemical experi-ments were used to provide evidence of intermediates.
出处
《催化学报》
SCIE
EI
CAS
CSCD
北大核心
2014年第11期1864-1873,共10页
基金
国家自然科学基金(21103207
21133011)~~
关键词
醇
需氧氧化
四氮配体
铜
2
2
6
6-四甲基哌啶-氮-氧自由基
Alcohol Aerobic oxidation Tetradentate nitrogen ligand Copper 2,2,6,6-tetramethylpiperidine-1-oxyl
