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帕金森病平衡障碍的研究进展 被引量:10

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摘要 平衡障碍与静止性震颤、运动迟缓和肌僵直共为帕金森病四主征,是病程进展到Hoehn-Yahr (H&Y)3级的指征,也是导致患者功能障碍和生活质量下降最重要的原因之一.临床上以平衡障碍-步态异常为主要症状的帕金森病患者往往具有病程进展较快,出现抑郁、认知障碍、跌倒及残疾的概率较高的特点.虽然跌倒等平衡障碍的症状常在病程晚期出现,但是既往研究发现在帕金森病早期亦可以出现身体摇摆异常,即轻度的平衡功能失调,并随着病程的进展逐渐加重,增加发生跌倒的风险[1].当然,早期出现的平衡功能异常也可能预示着帕金森叠加综合征的出现,如核上性眼肌麻痹、多系统萎缩和路易体痴呆.在临床实践及科研工作中,人们常常忽略帕金森病的平衡障碍,因此,我们就帕金森病平衡障碍的流行病学、病理生理机制、相关影响因素及检测方法作一综述.
作者 岑姗姗 陈彪
出处 《中华神经科杂志》 CAS CSCD 北大核心 2014年第11期802-805,共4页 Chinese Journal of Neurology
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参考文献30

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