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脑心通干预糖尿病患者心脑血管病疗效评估 被引量:4

Evaluation of Naoxintong Efficacy for Treating Cardiovascular Events in Diabetic Patients
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摘要 目的:社区应用不同疗法治疗糖尿病患者,评估应用脑心通胶囊针对预防糖尿病心脑血管意外、实验室指标及干预颈动脉内层中膜厚度的临床疗效。方法:67例糖尿病患者分为2组予延续西药降糖、降脂等治疗。中药组应用脑心通胶囊治疗,对照组不应用中药汤剂或中成药治疗。持续治疗1年后从心脑血管不良事件、颈动脉彩超结果及血糖、血脂、糖化血红蛋白等生化指标等方面,评估其治疗效果。结果:与治疗前相比,中药组与对照组血脂较治疗前差异有统计学意义(P<0.05),且2组间比较差异有统计学意义(P<0.05)。中药组在IMT、血糖、糖化血红蛋白等指标方面治疗前后比较差异有统计学意义(P<0.05),而对照组治疗前后比较差异无统计学意义(P>0.05),2组比较差异有统计学意义(P<0.05),中药组心脑血管不良事件较对照组少。结论:社区的糖尿病患者应用脑心通胶囊治疗有益于血糖、血脂控制,血管内皮保护及预防心脑血管不良事件。 Objective:To observe cardiovascular events,changes of laboratory parameters,and carotid internal media thickness in dia-betic patients applied with different treatment regimens.Methods:Sixty-seven patients were divided into 2 groups,both groups were trea-ted with western medicines,the Chinese medicine group was treated with Naoxintong in addition.After 1 years of continuous treatment, therapeutic effect was evaluated based on incidence of cardiovascular events,IMT,blood glucose and lipids,glycated hemoglobin and oth-er biochemical indicators.Results:There were significant blood lipid differences after treatment in both treatment groups (P 〈0.05),and the difference was significant between 2 groups (P 〈0.05).There was statistical significance before and after treatment in Chinese medi-cine group in IMT,blood glucose,glycosylated hemoglobin protein index (P 〈0.05),while the control group before and after treatment had no significant difference (P 〉0.05),there was significant difference between 2 groups (P 〈0.05).The Chinese medicine group had less cardiovascular event incidence compared with the control group.Conclusion:Naoxintong has good effect for treating blood glucose and blood lipids which helps to prevent incidence of cardiovascular events in diabetic patients.
作者 刘焱
出处 《世界中医药》 CAS 2014年第11期1491-1493,共3页 World Chinese Medicine
关键词 糖尿病 颈动脉内层中膜厚度 心脑血管不良事件 中医治疗 Diabetes Carotid internal media thickness Cardiovascular events Treatment of traditional Chinese Medicine
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