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安尔碘法胸膜固定治疗原发性自发性气胸的效果 被引量:3

Efficacy of video-assisted thoracoscopic entoiodine pleurodesis on primary spontaneous pneumothorax
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摘要 背景:有学者认为对于易复发的原发性自发性气胸应积极行胸腔镜手术治疗,并且术中行胸膜固定能有效降低术后复发率。目的:探讨安尔碘法胸腔镜治疗原发性自发性气胸的可靠性及有效性。方法:纳入原发性自发性气胸患者64例,其中男46例,女18例,年龄15-30岁,随机均分为试验组与对照组,两组均进行胸腔镜手术治疗,其中试验组关闭切口前应用干纱布蘸取安尔碘涂抹整个胸腔,对照组未应用安尔碘。比较两组患者的手术时间、术中出血、术后引流量、术后漏气时间,术后拔管时间、术后并发症发病率及术后1年气胸的复发率。结果与结论:两组手术时间、术中出血、术后漏气时间、术后拔除胸管时间及术后并发症的发生率比较差异均无显著性意义(P>0.05);试验组术后引流量较对照组明显增加(P<0.05),但未造成需医学干预的后果;试验组术后1年复发率低于对照组(P<0.05)。结果表明胸腔镜手术过程中利用安尔碘涂擦壁层胸膜行胸膜固定,是一种预防原发性自发性气胸术后气胸复发的可靠且有效的治疗方式。 BACKGROUND:Some scholars believe that for primary spontaneous pneumothorax thoracoscopic surgery and intraoperative pleurodesis can effectively reduce the recurrence rate. OBJECTIVE:To study the reliability and validity of video-assisted thoracoscopic entoiodine pleurodesis for treatment of primary spontaneous pneumothorax. METHODS:Videothoracoscopy procedures were performed on 64 patients with primary spontaneous pneumothorax, including 46 males and 18 females, with an age ranging from 15 to 30 years. According to the use of pleurodesis, the patients were randomly divided into two groups:experimental group and control group. In the control group, no entoiodine was used;while in the experimental group, entoiodine dipped gauze was used on the visceral pleura. The operation time, intraoperative bleeding, postoperative drainage, postoperative leakage time, postoperative extubation time, postoperative complications and the recurrence rate of pneumothorax within 1 year after operation were compared between two groups. RESULTS AND CONCLUSION:No significance was found in the operation time, intraoperative bleeding, postoperative leakage time, postoperative extubation time and postoperative complications between the two groups (P〉0.05). Although the experimental group had significantly more postoperative drainage volume than the control group (P〈0.05), there were no consequences of medical intervention. Video-assisted thoracoscopic entoiodine pleurodesis could significantly reduce the recurrence rate of pneumothorax in 1 year after operation (P〈0.05). The results show that video-assisted thoracoscopic operation with entoiodine is a reliable and effective&amp;nbsp;method to reduce the recurrence of pneumothorax after operation in patients with primary spontaneous pneumothorax.
出处 《中国组织工程研究》 CAS CSCD 2014年第43期7007-7011,共5页 Chinese Journal of Tissue Engineering Research
关键词 胸腔镜 陶膜固定术 气胸 thoracoscopes pleurodesis pneumothorax
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