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子宫动脉栓塞术和全身甲氨蝶呤治疗剖宫产术后瘢痕妊娠的疗效比较 被引量:14

Comparison of the efficacy of uterine artery embolization and systematic methotrexate on cesarean scar pregnancy
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摘要 目的评价子宫动脉栓塞术在剖宫产术后瘢痕妊娠中的临床疗效。方法回顾性分析67例剖宫产术后瘢痕妊娠患者的临床资料。将患者分为栓塞组(n=35)和甲氨蝶呤组(n=32),2组患者均行宫腔镜手术治疗,栓塞组行双侧子宫动脉栓塞术,甲氨蝶呤组肌肉注射甲氨蝶呤。观察2组患者术中出血量、住院时间、术后血人绒毛膜促性腺激素(HCG)转阴时间、月经恢复时间、病灶消失时间等指标,并进行比较。结果 2组患者治疗后血HCG转阴时间、住院时间、病灶消失时间及术中出血量比较,差异均有统计学意义(P<0.05);月经恢复时间2组间比较差异无统计学意义(P>0.05)。2组不良反应发生情况比较差异无统计学意义(P>0.05)。结论子宫动脉栓塞联合宫腔镜下清宫术治疗剖宫产术后瘢痕妊娠安全、有效。 Objective To evaluate the efficacy of uterine artery embolization in treating of cesarean scar pregnancy.Methods The clinical data of sixty-seven women with pregnancy within cesarean scar were analyzed retrospectively. All patients were divided into embolization group(n = 35)and methotrexate group(n = 32). All patients underwent hysteroscopic surgery;the patients in embolization group and methotrexate group were given uterine artery embolization and methotrexate( intramscular injection) respectively. The intraopertative blood loss,hospitalization time,the time of serum human chorionic gonadotroph(HCG) resolution,the recover time of menses,and the time of lesion disappearance were analyzed and compared between the two groups. Results There were statistic difference of the time of serum HCG resolution,hospitalization time,the time of lesion disappearance,and intraopertative blood loss between the two groups after treatment( P〈0. 05). There was no statistic difference of he recover time of menses between the two groups(P〉0. 05). There was no statistic difference of incidence of adverse reaction between the two groups( P〉0. 05). Conclusion The uterine artery embolization combined with hysteroscopic surgery for treatment of cesarean scar pregnancy is safe and effective.
出处 《新乡医学院学报》 CAS 2014年第11期925-927,共3页 Journal of Xinxiang Medical University
关键词 剖宫产术后瘢痕妊娠 子宫动脉栓塞术 甲氨蝶呤 宫腔镜治疗 cesarean scar pregnancy uterine artery embolization methotrexate hysteroscopic surgery
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  • 1Moschos E, Srcenarasimhaiah S, Twickler D M. First-trimester di- agnosis of cesarean scar ectopic pregnancy[ J]. J Clin Ultrasotmd, 2008,36(8) :504-511. 被引量:1
  • 2Jurkovic D, Hillaby K, Woelfer B, et al. First-trlmester diagnosis and management of pregnancies implanted into the lower uterine segment cesarean section scar [ J ]. Ultrasound Obstet Gynecol, 2003,21 (3) :220-227. 被引量:1
  • 3Seow K M, Huang L W, Lin Y H, et al. Cesarean scar pregnancy: issues in management [ J 1. Ultrasound Obstet Gynecol, 2004,23 (3) :247-253. 被引量:1
  • 4Rotas M A, Haberman S, Levgur M. Cesarean scar ectopic pregnan- cies : etiology, diagnosis, and management [ J ]. Obstet Gyneeol, 2006,107 (6) : 1373-1381. 被引量:1
  • 5Rosen T. Placenta accreta and cesarean scar pregnancy:overlooked cost of the rising cesarean section rate[ J]. Clin Perinatol,2008,35 (3) :519-529. 被引量:1
  • 6Timor-Tritsch I E, Monteagudo A, Santos R, et al. The diagnosis, treatment, and follow-up of cesarean scar pregnancy[ J]. Am J Ob- stet Gyneeo1,2012,207 ( 1 ) : e1-e13. 被引量:1
  • 7蔡美玲,祝亚平,万小平.子宫下段剖宫产切口瘢痕处妊娠诊治进展[J].现代妇产科进展,2009,18(3):232-234. 被引量:71
  • 8Yang X Y, Yu H, Li K M, et al. Uterine artery embolisation com- bined with local methotrexate for treatment of caesarean scar preg- nancy [ J ]. B JOG,2010,117 ( 8 ) :990-996. 被引量:1
  • 9Wang J H, Xu K H, Lin J. Methotrexate therapy for cesarean sec- tion scar pregnancy with and withoutsuction curettage [ J ]. Fertil Steril , 2009 , 92 ( 4 ) :1208-1213. 被引量:1
  • 10陈正云,张信美,许泓,张晶,黄秀峰.宫腔镜联合子宫动脉栓塞术终止剖宫产术后子宫瘢痕妊娠的疗效与安全性[J].中华妇产科杂志,2011,46(8):591-594. 被引量:107

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  • 1曹泽毅.中华妇产科学[M].2版.北京:人民卫生出版社,1999.584. 被引量:38
  • 2卢丽娟,伍荣,雷俊华,李萍.阴道超声对剖宫产术后切口妊娠5例诊断分析[J].中国误诊学杂志,2007,7(28):6919-6920. 被引量:8
  • 3Rotas M A, Haberman S, Levgnr M. Cesarean scar ectopic pregnancies : etiology, diagnosis, and management [ J ]. Obstetrics & Gynecology, 2006, 107(6): 1373-1381. 被引量:1
  • 4Ko JK, Li RH, Cheung VY. Caesarean scar pregnancy: a 10-year experience. Aust NZ J Obstet Gyn, 2015, 55(1):64-69. 被引量:1
  • 5He M, Chen MH, Xie HZ, et al. Transvaginal removal of ectopic pregnancy tissue and repair of uterine defect for caesarean scar pregnancy. B JOG, 2011, 118(9):1136-1139. 被引量:1
  • 6范光升,刘欣艳,金力,等.介入技术在终止剖宫产后子宫下段疤痕早期妊娠的应用.中国计划生育学杂志,2010,23(7):144-148. 被引量:1
  • 7Bhojwani D, Sabin ND, Pei D, et al. Methotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia [ J ]. J Clin Onoo1,2014,32(9) :949 -959. DO1:10.1200/]CO. 2013.53. 0808. 被引量:1
  • 8Buizer AI, de Sonneville LM, Veerman AJ. Effects of chemotherapy on neurocognitive function in children with acute lymphoblastie leukemia:a critical review of the literature [ J ]. Pediatr Blood Cancer ,2009,52 (4) : 447 - 454. DOI : 10. 1002/pbc. 21869. 被引量:1
  • 9Young M, Kim JS, Jang S, et al. Acute treatment with methotrexate in- duces hippocampal dysfunction in a mouse model of breast cancer [ J ]. Brain Res Bull,2012,89 ( 1 - 2 ) :50 - 56. DOI: 10. 1016/j. brainres- bull. 2012.07. 003. 被引量:1
  • 10Kuznetsov JN, Leclerc GJ, Leclerc GM, ctal. AMPK and Akt determine apoptotic cell death following perturbations of one-carbon metabolism by regulating ER stress in Acute Lymphoblastic Leukemia [ J ]. Mol Cancer Ther,2011,10 (3) :437 - 447. DOI : 10.1158/1535-7163. MCT-10-0777. 被引量:1

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