摘要
目的探讨鼻咽癌放射治疗后所致脑干梗死的临床特点。方法报道1例鼻咽癌放射治疗后9年出现脑干梗死的患者,结合复习文献对该病的临床表现、影像学特点以及可能的发病机制予以分析。结果患者男性,42岁。急性起病,临床表现为左侧肢体无力和复视,既往有鼻咽癌放射治疗史,无明显血管危险因素。头颅MRI示脑干梗死,CTA示双侧大脑后动脉管腔狭窄。结论该患者脑干梗死可能与鼻咽癌放射治疗相关。
Aim To investigate the clinical characters of brain stem infarction after radiation for nasopharyngeal carcinoma. Methods A patient with brain stem infarction 9 years after radiotherapy for nasopharyngeal carcinoma was reported. The clinical, imaging feature and pathogenesis were retrospectively analyzed with relevant documents. Results A 42-year-old male had acute-onset right-sided hemiparesis and diplopia. The paitent had a history of cranial radiation therapy for nasopharyngeal carcinoma and had no significant vascular risk factors. Cranial MR imaging showed brain stem infarction and CTA showed a stenosis of the bilateral posterior cerebral artery. Brain stem infarction in this patient was likely associated with the radiotherapy. Conclusion Radiotherapy is the first choice of treatment for nasopharyngeal carcinoma, however, it may induce brain stem infarction.
出处
《中国临床神经科学》
2014年第5期535-538,共4页
Chinese Journal of Clinical Neurosciences
关键词
鼻咽癌
放射疗法
脑干梗死
放射性脑病
nasopharyngeal carcinoma
radiotherapy
brain stem infarction
radiation encephalopathy
