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丙泊酚复合芬太尼在无痛人工流产术中的临床麻醉效果观察 被引量:11

The anesthesia effect of propofol and fentanyl in painless artificial abortion operation
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摘要 目的研究分析在无痛人工流产术中使用丙泊酚复合芬太尼的麻醉效果,为其临床应用和研究提供科学依据。方法回顾性分析2012年4月至2013年4月本院接受无痛人工流产术治疗的110例患者的临床资料,以患者入院日期的单、双号为区分标准,将患者随机分为两组,对照组55例,采用单纯丙泊酚麻醉,观察组55例,采用丙泊酚复合芬太尼麻醉,严密监测两组患者术前、术中和术后的呼吸频率、心率、血压、血氧饱和度等指标,记录并统计分析患者术后苏醒时间、不良反应发生情况、丙泊酚的使用剂量等。结果术后两组患者的呼吸频率、血氧饱和度、心率均明显下降,对照组患者的收缩压水平下降程度明显,但两组比较差异无显著性(P>0.05);观察组患者的临床疗效优于对照组,差异具有显著性(P<0.05);观察组患者治疗期间出现的不良反应少于对照组,差异具有显著性(P<0.05)。结论对接受无痛人工流产术的患者采取丙泊酚复合芬太尼麻醉,可达到明显的镇痛、麻醉效果,且术后恢复意识所需时间较短,丙泊酚用量少,术后不良反应少,颇具临床价值,值得重视和推广。 Objective Analysis of anesthetic effect of propofol combined with fentanyl in painless artiifcial abortion operation, and provide the scientific evidence for its clinical application and study. Method Retrospective analysed in April 2012 to April 2013, the clinical data of 110 cases accepted treatment of painless operation patients in our hospital, the number, date of admission of the patients with even numbers into standard, 110 patients were divided into two groups by using the simple random method, 55 patients in control group were treated with propofol alone, 55 cases in treatment group were treated with propofol and fentanyl, close monitoring patients of heart rate, blood pressure, respiratory rate, oxygen saturation and other indicators before operation, during operation and post operation, and recorded the use of dose recovery time, adverse reactions, propofol in patients with postoperative, used statistical software to analyse data. Result RR, SpO2, HR decreased signiifcantly in all patients, control group with systolic blood pressure levels decreased signiifcantly, but the difference between the two groups was not obvious, the difference had no statistical signiifcance (P〉0.05);anesthetic efifcacy of treatment group was better than control group, the two groups had signiifcant difference (P 〈0.05);the adverse reaction of treatment group was less than control group, with statistically signiifcant difference between two groups (P〈 0.05). Conclusion For patients adopted painless artificial abortion operation, propofol and fentanyl anesthesia, can achieve signiifcant analgesic, anesthetic effect, and postoperative awake time are shorter, less dosage of propofol, less postoperative adverse reaction, worthy of promoting.
作者 乔英 武海龙
出处 《中国医学前沿杂志(电子版)》 2014年第9期111-114,共4页 Chinese Journal of the Frontiers of Medical Science(Electronic Version)
关键词 丙泊酚 芬太尼 无痛人工流产术 麻醉效果 清醒时间 Propofol Fentanyl Painless artiifcial abortion operation Anesthesia Awake time
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