摘要
目的：探讨江苏盐城地区不同年龄宫颈癌及癌前病变患者的血液检查、临床特征和治疗情况等,以便正确了解宫颈癌及癌前病变的临床特征及规律。方法：对2011~2013年住院的260例宫颈癌及癌前病变患者的临床资料进行回顾性分析,根据年龄分为≤45岁组和〉45岁年龄组。结果：≤45岁组的宫颈癌及癌前病变患者临床症状以接触性出血为主,而〉45岁组临床症状以阴道不规则流血为主;≤45岁组临床分期以癌前病变和宫颈癌0~Ⅰ期为主,所占比例分别为43.2%和32.8%,〉45岁组临床分期以宫颈癌Ⅱ期为主,占56.1%;两组组织病理学类型及分级、淋巴转移之间比较,差异无统计学意义（P〉0.05）;≤45岁组患者单纯手术治疗为主,且保留卵巢功能所占比例较高,而〉45岁组患者以手术结合放、化疗辅助治疗为主,且以广泛全子宫双附件切除和盆腔淋巴结清扫术所占比例较高。结论：正确了解不同年龄宫颈癌及癌前病变患者临床特征及其规律,对提高早期诊断和改善预后有重要意义。
Objective： To explore blood examination, clinical characteristics and treatment of patients in different age groups with cervical cancer and cervical precancerous lesion in Yancheng, Jiangsu, understand the clinical characteristics and regularities of cervical cancer and cervical precancerous lesion correctly. Methods： The clinical data of 260 hospitalized patients with cervical cancer and cervical precancerous lesion from 2011 to 2013 were analyzed retrospectively, then the patients were divided into ≤45 -year- old group and 〉45 - year - old group. Results： The main clinical symptom was contact bleeding in ≤45 - year - old group, while vaginal irregular bleeding was the main clinical symptom in 〉 45 - year - old group. In ≤ 45 - year - old group, stage 0 - Ⅰ was the main type in patients with cervical cancer and cervical precancerous lesion, accounting for 43.2% and 32. 8% , respectively ; in 〉 45 - year - old group, stage Ⅱ was the main type in patients with cervical cancer and cervical precancerous lesion, accounting for 56. 1%. There was no statistically significant difference in pathological types and grades, lymph node metastasis between the two groups （P 〉 0. 05） . Pure surgical treatment was the main therapy in ≤45 - year - old group, the proportion of preserving ovarian function was high ; surgery combined with chemotherapy and radiotherapy were the main therapies in 〉 45 - year - old group, the proportions of total hysterectomy and adnexal removal and pelvic lymph nodes dissection were high. Conclusion ： Correctly understanding the clinical characteristics and regularities of cervical cancer and cervical precancerous lesions among patients in different age groups has important significance to improve early diagnosis and prognosis.
出处
《中国妇幼保健》
CAS
北大核心
2014年第33期5377-5379,共3页
Maternal and Child Health Care of China
基金
盐城市医学科技发展计划项目〔YK2013060〕
江苏省大学生实践创新训练计划立项项目〔201312682001Y〕
江苏省青蓝工程项目〔2012〕
江苏省六大人才高峰项目〔2013-WSW-053〕
关键词
宫颈癌
癌前病变
临床分析
Cervical cancer
Precancerous lesion
Clinical analysis
