摘要
目的探讨硫酸镁在功能性鼻内镜手术中的应用价值。方法 ASAⅠ或Ⅱ级择期鼻内镜手术患者60例,随机分为两组,每组30例,A组（异氟醚组）：需降压时加大异氟醚吸入浓度至3%~4%;不需低血压时,逐渐减少异氟醚吸入浓度。B组（硫酸镁组）维持异氟醚吸入浓度至1%~2%需降压时,静脉推注硫酸镁40~60 mg/kg（1~2 min内推注完）,当MAP降至60 mmHg左右后.改为2 mg/kg·min维持。直至不需降压时停药。记录各组麻醉前、降压后10、20、30 min平均动脉压、心率、术中出血量、术野评级、手术时间、术后血镁情况。并记录降压起效、维持及复压时间。结果与异氟醚组比较,硫酸镁组HR慢、出血量少、手术时间短、术野清晰度评分低（P〈0.05）;降压维持及复压时间差异有统计学意义（P〈0.05）。结论硫酸镁控制性降压可减少功能性鼻内镜手术的出血量,保持术野清晰,缩短手术时间,具有较高的安全性及临床使用价值。
Objective To observe the value of magnesium sulfate in nasal endoscopic surgery. Method Sixty ASA ⅠorⅡ Patients were randomly divided into two groups. Group A（ Isoflurane group） ： The concentration of isoflurane was increased when it need to induce hypotension. Group B（ Magnesium sulfate group） ： Those in group B were given magnesium sulfate of 40 ~ 60 mg·kg bolus,followed by continuous infusion of 2mg·kg- 1·min-1 from maintain MAP at 55 ~ 65 mmHg to stop hypotension. MAP,HR,amount of blood loss,clear visual field of operation and the operation time were observed and compared between two groups. Result The difference of HR,amount of blood loss,the operation time and clear visual field of operation between two groups was significant（ P〈 0. 05）,The difference of MAP between two groups showed no statistic difference（ P〈 0. 05）. Conclusion The induced hypotension with magnesium sulfate can produce time of operation and amount of blood loss decreased. It can safely applied to the in clinical practice.
出处
《内蒙古医学杂志》
2014年第9期1042-1045,共4页
Inner Mongolia Medical Journal
关键词
硫酸镁
降压
控制性
内镜术
magnesium sulfate
hypotension
controlled
endoscopy
