摘要
目的：探讨对老年中央型肺癌患者采用支气管肺动脉成形术的疗效。方法78例老年中央型肺癌患者按照数字表法随机分为两组各39例，观察组采用支气管肺动脉成形术，对照组采用全肺切除术。比较两组患者1、3、5年生存率。统计术后并发症的发生率。测定术后3个月的肺功能变化。结果对照组术后1、3、5年生存率分别为66．7％（26/39）、46．2％（18/39）、30．8％（12/39），观察组分别为79．5％（31/39）、56.4％（22/39）、38．5％（15/39），两组差异均有统计学意义（χ^2=6．17、7．06、4．82，均P＜0．05）；对照组术后有11例（28．2％）发生并发症，观察组术后有4例（10．1％）发生并发症，两组差异有统计学意义（χ^2=6．32， P＜0．05）；两组治疗前FEV1、FVC、PEF差异均无统计学意义（t＝0．72、0．11、0．39，均P＞0．05），治疗后两组FEV1、FVC、PEF均得到明显改善（t＝5．92、7．92、4．11、7．01、5．99、6．82，均P＜0．01），且观察组改善程度明显优于对照组（t＝2．84、2．77、3．28，均P＜0．05）。结论支气管肺动脉成形术治疗老年中央型肺癌疗效显著，并发症少，可以进一步改善肺功能。
Objective To study the effectiveness of bronchial pulmonary artery angioplasty in elderly patients with central lung.Methods 78 elderly patients with central lung were randomly divided into two groups,the control group（n=39） and the observation group（n=39）.The patients in the control group were operated through pneumonectomy,while the observation group was operated through bronchial pulmonary artery angioplasty.1,3,5-year survival rates were compared.Incidence of postoperative complications were counted.The changes in pulmonary func-tion after 3 months were determined.Results The survival rates in the control group were 66.7%（26/39）,46.2%（18/39）,30.8%（12/39） and 79.5%（31/39）,56.4%（22/39）,38.5%（15/39） in the observation group.The survival rates of the observation group were significantly higher （χ^2=6.17,7.06,4.82,all P〈0.05）.The control group had 11 cases of complications after surgery,the rate was 28.2%.The observation group had 4 cases of postoper-ative complication,the rate was 10.1%.The incidence of complications in the observation group was significantly less than that of the control group （χ^2=6.32,P〈0.05）.There was no significant difference （t=0.72,0.11,0.39,all P〉0.05） between the two groups before treatment about FVC,PEF and FEV1.After treatment,FEV1,FVC,PEF were significantly improved （t=5.92,7.92,4.11,7.01,5.99,6.82,all P〈0.01）.The degree of improvement in the observation group was higher than that of the control group （t=2.84,2.77,3.28,all P〈0.05）.Conclusion Bron-chial pulmonary artery angioplasty has significantly fewer complications,can be further improved lung function in eld-erly patients with central lung cancer.
出处
《中国基层医药》
CAS
2014年第22期3373-3375,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
肺肿瘤
支气管成形术
肺动脉成形术
Lung neoplasms
Bronchial angioplasty
Pulmonary artery angioplasty
