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猪毛色基因黑色素受体1的基因型分析 被引量:2

The Genotype Analysis of Coat Color Gene MC1R in Swine
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摘要 为检测黑色素受体1(melanocortin receptor 1,MC1R)基因型在不同毛色猪种中的分布,研究该基因在猪毛色决定中的地位和作用,本试验使用PCR-SSCP和PCR-RFLP方法对军牧1号白猪、杜洛克猪、西藏小型猪和大白猪的MC1R基因型进行了检测。结果显示,长白猪、大白猪存在nt894insCC和G1197A突变;杜洛克猪存在G668C、C1318T和G1554A突变;西藏小型猪存在C1318T和G1554A突变,而在nt894insCC位点则表现出其他基因型。通过对4个猪种的MC1R基因型的检测,为研究MC1R基因对毛色的作用机理奠定了基础。 For analysis melanocortin receptor 1 (MCIR) genotype in swine spices with different coat color and study the gene functions on swine coat color. This research analysed the genotype of MCIR in Junmu 1 White pigs. Durocs pigs. Tibet mini-pigs and Large White pigs with PCR-SSCP and PCR-RFLP technique. The result showed that Junmu 1 White pigs and Large White pigs presented mutation on nt894insCC and G1l97A site. Durocs pigs presented mutation on G668C. C1318T. and G1554A site. Tibet mini-pigs presented mutation on C1318T and G1554A site, with a different genotype on nt894insCC site. The MCIR genotype result provided a basis for studying MCIR regulation mechanism to swine coat color.
出处 《中国畜牧兽医》 CAS 北大核心 2014年第11期44-49,共6页 China Animal Husbandry & Veterinary Medicine
基金 吉林省科技厅农业处资助项目(20120224) 长春市科技局农业处资助项目(2012231)
关键词 MC1R基因 毛色 MCIR gene coat color swine
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  • 1于云柱,何奕多,刘丽,王秀娟,刘情,邓卫东.黑素皮质素受体1(MC1R)基因的研究进展[J].中国畜牧兽医,2010,37(6):232-233. 被引量:25
  • 2师科荣,王爱国,李宁,邓学梅.中国地方猪种黑素皮质激素受体1基因(MC1R)的单核苷酸多态性[J].中国科学(C辑),2004,34(2):144-149. 被引量:9
  • 3顿桂玲..猪黑素皮质素受体1(MC1R)基因与毛色表型相关及5’UTR变异研究[D].河北农业大学,2007:
  • 4Deng S H, Gao J, Ren J, et al. Studies of the relationship ofmelanocortin receptor 1 (MC1R) gene with coat color phenotype in pigsI-J]. Acta Genetica Siniea, 2003, 30(10) :949-954. 被引量:1
  • 5顿桂玲,李祥龙,曹洪战,周荣艳,李兰会.Variations of Melanocortin Receptor 1 (MC1R) Gene in Three Pig Breeds[J].Journal of Genetics and Genomics,2007,34(9):777-782. 被引量:8
  • 6Kathleen G, Mountjoy L, Robbins S. The cloning of a family of genes that encode the melanocortin receptor[J]. Science, 1992, 257(5074) :1248-1251. 被引量:1
  • 7Kijas J W, Moller M, Plastow G, et al. A frameshift mutations in MCIR and a high frequency of somatic reversions cause black spotting inpigs[J]. Genetics, 2001, 158 (2):779-785. 被引量:1
  • 8Mao H R, Ren J, Ding N S, et al. Genetic variation within coat color genes of MC1R and ASIP in Chinese brownish red Tibetan pigs[J]. Animal Science Journal, 2010, 81:630-634. 被引量:1
  • 9Michael M O, Mlynn L, Brent D W, et al. Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo[J]. Gene and Development, 1998, 12: 316-330. 被引量:1
  • 10Silvers W K. The coat colors of mice. A model for mammalian gene action and interaction[M]. New York: Springer Verlag, 1979. 被引量:1

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