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患儿EB病毒感染性咽炎与肠系膜淋巴结炎的相关性研究

Relationship between EB virus-induced infective pharyngitis in children and mesenteric lymphadenitis
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摘要 目的分析患儿EB病毒感染性咽炎与肠系膜淋巴结炎的关系,为临床诊断提供参考。方法选取医院自2013年1-12月收治的咽炎且有消化道症状患儿300例,对其进行实验室检查,其中EB病毒感染阳性患儿135例为观察组;EB病毒感染阴性患儿165例为对照组,对两组患儿进行临床检查,对比观察其肠系膜淋巴结数目、大小及血流情况,分析汇总。结果肠系膜淋巴结炎发病率观察组为25.2%、对照组为7.2%,差异有统计学意义(P<0.01);观察组淋巴结平均大小为(13.4±3.1)mm、对照组为(4.7±1.1)mm;观察组41例患儿出现>10mm的淋巴结、对照组有13例;观察组48例患儿同一超声切面淋巴结个数>3个、对照组为17例;观察组点状血流46例、线状血流78例、无血流36例,相比于对照组21、70例和74例,以上差异均有统计学意义(P<0.01)。结论患儿EB病毒感染性咽炎可并发肠系膜淋巴结炎,两者相关性较大,应根据患儿临床表现、实验室检查及超声检查结果进行综合分析。 OBJECTIVE To analyze the relationship between the EB virus‐induced infective pharyngitis in children and mesenteric lymphadenitis so as to provide guidance for clinical diagnosis .METHODS A total of 300 children with pharyngitis and gastrointestinal symptoms ,who were treated in the hospital from Jan 2013 to Dec 2013 ,were enrolled in the study ,then the laboratory examination was conducted ;135 children who were positive for EB virus infection were assigned as the observation group ,while 165 children who were negative for EB virus infection were set as the control group ,the clinical examination was performed for the two groups of children ;the number and size of the mesenteric lymph nodes as well as the blood flow were observed and compared between the two groups . RESULTS The incidence of mesenteric lymphadenitis was 25 .2% in the observation group ,7 .2% in the control group ,the difference was statistically significant (P〈0 .01) .The average size of the mesenteric lymph nodes of the observation group was (13 .4 ± 3 .1)mm ,the control group (4 .7 ± 1 .1)mm .There were 41 children with the lymph nodes more than 10mmm in the observation group and 13 children in the control group .There were 48 chil‐dren with the number of lymph nodes on the same ultrasound section more than 3 in the observation group and 17 children in the control group .There were 46 cases of punctuate blood stream in the observation group and 21 cases in the control group ;there were 78 cases of linear blood stream in the observation group and 70 cases in the control group;there were 36 cases without blood stream in the observation group and 74 cases in the control group ,the differences were statistically significant (P〈0 .01) .CONCLUSIONS The EB virus‐induced infective pharyngitis in the children can be complicated with the mesenteric lymphadenitis ,and there is close relationship between the two .It is necessary to conduct the comprehensive analysis according to the clinical manifestations as well as the re‐s
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2014年第22期5670-5672,共3页 Chinese Journal of Nosocomiology
基金 浙江省医药卫生计划基金资助项目(2011KYA026)
关键词 患儿 EB病毒 咽炎 肠系膜淋巴结炎 相关疾病 Child EB virus Pharyngitis Mesenteric lymphadenitis Related disease
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