摘要
目的:探讨早期乳腺癌前哨淋巴结(sentinel lymphnode,SLN)阴性患者、1枚阳性SLN患者与2枚以上阳性SLN患者的非前哨淋巴结(non-sentinel lymphnode,NSLN)转移状况。方法:对90例T1-2N0M0乳腺癌患者应用美蓝为示踪剂行前哨淋巴结活检术(sentinel lymphnode biopsy,SLNB),进再行常规腋窝淋巴结清扫术(axillary lymph node dissection,ALND),根据检查结果将患者分成SLN(-)组、SLN(+)=1组及SLN(+)≥2组,并对各组的NSLN阳性率进行比较。结果:32例SLN(-)组检出NSLN阳性1例,阳性率3.1%,39例SLN(+)=1组检出NSLN阳性4例,阳性率为10.3%,19例SLN(+)≥2组检出NSLN阳性9例,阳性率为47.4%,SLNB检查假阴性1例,准确率为96.9%;SLN(+)=1组的NSLN阳性率略高于SLN阴性组,但差异无统计学意义P>0.05;SLN(+)≥2组患者的NSLN阳性率显著高于SLN(-)组及SLN(+)=1组,差异均具有统计学意义P<0.05。结论:研究结果提示1枚SLN阳性患者可仅行SLNB免行ALND,但≥2枚SLN阳性患者则需常规行ALND。
Objective：To explore the early sentinel lymph node in breast cancer （ sentinel, lymphnode, SLN） non sentinel lymph node negative patients, 1 positive in SLN patients with more than 2 pieces of SLN patients with positive nodes （ non-sentinel lymph-node, NSLN） metastasis.Methods：90 T1-2N0M0 patients with breast cancer using methylene blue as tracer for sentinel lymph node biopsy （ sentinel lymphnode biopsy, SLNB ） , and enter the routine axillary lymphadenectomy （ axillary lymph node dissection, ALND） , according to the test results of the patients were divided into SLN （ -） group, =1 group and SLN （ ＋） SLN （ ＋） ≥2 groups, and each group of NSLN positive rates were compared.Results：32 cases of SLN （-） group was 1 cases with positive NSLN, the positive rate was 3.1%, 39 cases of SLN （＋） =1 was detected in 4 cases of NSLN positive, the positive rate was 10.3%, 19 ca-ses of SLN （＋） ≥2 group were NSLN positive in 9 cases, the positive rate was 47.4%, SLNB examination of 1 cases of false nega-tive, the accuracy rate was 96.9%;the positive rate of SLN （＋） NSLN in =1 group was higher than that in SLN negative group, but no significant difference between P＆amp;gt;0.05;SLN （ ＋） ≥ NSLN positive rate in patients of the 2 groups were significantly higher than that of SLN （-） group and SLN （＋） in =1 group, the differences were statistically significant P＆amp;lt;0.05.Conclusion：The results suggest that the 1 SLN positive patients can only SLNB free ALND, patients with positive but≥2 SLN requires routine ALND.
出处
《牡丹江医学院学报》
2014年第5期27-29,共3页
Journal of Mudanjiang Medical University
基金
广东省韶关市医学科研基金项目(2013CX/K205)
广东省韶关市卫生局医学科研项目(Y13169)
