摘要
目的观察拉莫三嗪治疗脑血管病后继发癫痫不良反应及疗效。方法选择佛山市南海区人民医院收治的160例脑血管病后继发癫痫患者,随机将患者分为治疗组(80例)和对照组(80例),进行临床疗效对比。治疗组和对照组患者分别给予拉莫三嗪和卡马西平进行治疗。比较两组患者的总体疗效和不良反应发生情况,数据采用统计学软件SPSS17.0进行处理。结果治疗组患者在临床疗效和不良反应发生频率和严重程度方面均显著性较对照组患者好,差异均具有统计学意义(P<0.05)。结论拉莫三嗪抗脑血管病后继发癫痫的疗效明显,副作用小,值得进一步临床推广使用。
Objective To explore the effect of lamotrigine on patients with epilepsy after cerebrovascular disease. Methods A total of 160 patients with cerebrovascular disease in the Nanhai District people＇s hospital were taken as subjects. They were randomly divided into 2 groups,treatment group（ n = 80,tianmaqixiong decoction combinate with lamotrigine） and control group（ n = 80,lamotrigine）. The efficacy and adverse drug reactions（ ADR） of the 2 groups were compared,and all calculations were performed with SPSS version 17. 0. Results The effect of treatment group was better than that of the control group,and there is no obvious adverse effect. Conclusion Lamotrigine has obvious curative effect on epilepsy after cerebrovascular disease with mild adverse effects. It is worthy to popularize wildly.
出处
《今日药学》
CAS
2014年第10期756-758,共3页
Pharmacy Today
关键词
脑卒中
癫痫
拉莫三嗪
卡马西平
brain stroke
epilepsy
lamotrigine
carbamazepine
