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心力衰竭患者治疗中血清Copeptin水平的变化及与预后的关系 被引量:5

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摘要 目的:研究血清和肽素(Copeptin)在心力衰竭患者治疗前后的变化及其对病情评估、预后判断的价值。方法:130例慢性心力衰竭(CHF)患者为CHF组,健康对照组80例。2组分别测定血清Copeptin、N末端B型利钠肽原(NT-proBNP)水平、心脏超声检查;CHF组出院后3个月随访其心血管事件。结果:CHF组入院即刻血清Copeptin、NT-proBNP水平均高于对照组(均P<0.01);CHF组治疗7 d后血清Copeptin、NT-proBNP水平较入院时明显下降(均P<0.01);出院后3个月内,发生心血管事件患者的血清Copeptin、NT-proBNP水平在治疗前后均较高(P<0.05或P<0.01)。结论:CHF患者血清Copeptin、NT-proBNP水平升高,治疗后其水平明显下降;监测血清Copeptin浓度对CHF患者的危险分层及预后判断有一定价值。
出处 《内科急危重症杂志》 2014年第5期330-332,共3页 Journal of Critical Care In Internal Medicine
基金 上海市嘉定区科委课题基金(No:201117)
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参考文献7

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二级参考文献6

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共引文献61

同被引文献38

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