摘要
1970年代初期,中国科学工作者测定了亚洲地区第一个蛋白质晶体结构——猪胰岛素三方二锌晶体结构,成为中国结构生物学历史发展的起点.进入新世纪,该学科领域已进入国际前沿,展现出快速发展态势,正在迎来发展新时期.本篇评述包含"历史发展","现代化实验设施建设"和"深入生命世界,走进国际前沿——近年代表性研究成果集萃"三个主题节段,以较全视野反映结构生物学研究在中国的发展历程.
The determination by Chinese scientists in early 1970s of the crystal structure ofrhombohedral 2Zn pig insulin, the first protein crystal structure ever to be solved in Asia, marked the historical beginning of the structural biology research in China. Starting with the new century, research in structural biology in China experiences a rapid progress and facing a new development stage, placing her at the frontier of this field worldwide. This Special Column will conduct a panoramic review of the history and current status of structural biology research in China in three Sections, ＂The history＂, ＂The establishment of modern experimental facilities＂, and ＂The representative research fruits in recent years at the international frontier of life sciences＂.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
2014年第10期944-971,共28页
Progress In Biochemistry and Biophysics
关键词
结构生物学
历史回顾
structural biology, history, modem experimental facilities
