摘要
目的评价经尿道电切术（TUR）术后膀胱灌注治疗开始时间的不同对腺性膀胱炎治疗效果的影响。方法对2007年2月-2012年4月期间的95例有症状腺性膀胱炎患者的临床资料进行回顾性分析,按TUR术后灌注开始的时间不同对患者进行分组,A组37例术后24 h内开始灌注,B组58例术后1周开始灌注。首次灌注后的灌注频率为1次/周,灌注8次后改为1次/月,持续时间5～10个月。随访12～16个月,观察两组的治愈率、好转率、总有效性率、复发率和不良反应发生率。结果两组治愈率、好转率的差异无统计学意义（P〉0.05）,但两组在总有效率、复发率的差异有统计学意义（P〈0.05）;两组不良反应发生率的差异无统计学意义（P〉0.05）。结论腺性膀胱炎TUR术后短时间内（24 h内）即行膀胱灌注治疗可提高疗效,降低复发率,且其不良作用的发生率并不增加。
Objective To evaluate the clinical effect of early and deferred intravesical instillation in the treatment of cystitis glandularis after transurethral resection（TUR）. Methods We retrospectively analyzed the clinical data of 95 patients with cystitis glandularis during February 2007 to April 2012. Among them, 37 patients underwent the first intravesical instillation within 24 hours after transurethral resection（group A）, while the others underwent the same treatment within a week（group B）. Then, intravesical instillation in all patients were carried out once every week for 8 weeks, and after that, it was carried out once every month for 5 to 10 months. All the patients were followed up for 12 to 16 months. The cure rate, improvement rate, total effective rate, recurrence rate and incidence of adverse events associated with therapy were observed.Results Recovery rate, improvement rate, side effects were observed in group A and B respectively, and there was no signifi cant difference between the two groups（P〉 0.05）. But there was signifi cant difference in the total effective rate and recurrence rate（P 〈0.05）. Conclusion The fi rst intravesical instillation within 24 hours after transurethral resection in the treatment of cystitis glandularis can improve curative effect and lower recurrence rate, without the increase of side effects.
出处
《华西医学》
CAS
2014年第10期1841-1844,共4页
West China Medical Journal
关键词
腺性膀胱炎
早期膀胱灌注
疗效
Cystitis glandularis
Early intravesical instillation
Effect
