摘要
目的检测溃疡性结肠炎患者血清降钙素原的水平并研究其临床意义。方法选择溃疡性结肠炎患者为研究对象(UCS组),以正常健康人为对照(CON组),对比两组研究对象血清降钙素原的差异,比较其在不同临床病理因素中的差异并分析其相关性。结果 UCS组患者血清降钙素原水平显著高于CON组正常人(P<0.05)。溃疡性结肠炎患者血清降钙素原在性别、年龄和病变部位中无明显差异(均P>0.05),在病程和病变严重程度中的差异具有统计学意义(P<0.05),血清降钙素原与病程和病变严重程度呈正相关,病程越长、病情越严重,血清降钙素原水平越高。结论溃疡性结肠炎患者血清降钙素原水平显著高于正常健康人,其水平与病程和病情严章程度正相关,可作为溃疡性结肠炎病情及预后评估的标志物。
Objective To study the clinical significances and levels of serous procalcitonin in ulcerative colitis patients. Methods Patients with ulcerative colitis were selected for study（UCS group）, while the healthy people were as control group （CON group）. The correlation between serous procalcitonin and clinical pathological factors was analyzed. Result The serous procalcitonin in UCS group was significantly higher than in CON group（P＆lt;0.05）. There were no significances in gender, age and lesion location, while were in course of disease and severity. The serous adiponectin correlated positively with course of disease and severity（P＆lt;0.05）. Conclusion The serous procalcitonin in ulcerative colitis patients is significantly higher than in healthy people. The serous procalcitonin could act as a biomarker in disease condition and prognosis evaluation for ulcerative colitis.
出处
《中国医药指南》
2014年第31期26-27,共2页
Guide of China Medicine
关键词
溃疡性结肠炎
降钙素原
临床病理因素
临床意义
Ulcerative colitis
Procalcitonin
Clinical pathological factors
Clinical significances
