摘要
目的:对比分析坤宝丸与西药治疗更年期综合征临床疗效和激素水平。方法:98例更年期综合征妇女依照随机数字表法分为治疗组与对照组。每组各49例。观察组接受坤宝丸,每日两次,每次50粒,给药一个月。对照组接受雌激素疗法,利维爱2.5mg,每天1次,给药一个月。观察2组患者的临床症状、不良反应和激素水平。结果:对照组总有效率为91.8%。治疗组总有效率89.7%。2组的总有效率无明显差异(χ2=0.12,P<0.05)。与对照组比较,治疗组中FSH和LH变化幅度与对照组无明显差异(t=0.11,P>0.05),结论:坤宝丸治疗更年期综合征的临床疗效与西药利维爱无明显差异,在改善FSH和LH上,和利维爱无明显差异,不良反应小,临床具有一定的可行性。
Objective：To compare the clinical efficacy of Kunbao pill with western medicine in the treatment of menopaus-al syndrome and hormone levels.Methods：98 cases of women were randomly divided into a treatment group and a con-trol group according to random number table.There were 49 cases in each group.The observation group was received 50 Kunbao pills twice a day for a month.The control group was received estrogen therapy of 2.5mg Livial one time every day for one month.The clinical symptoms, adverse reactions and hormone levels were observed between two groups.Re-sults：The total effective rate was 91.8% in the treatment group.The total efficiency rate was 89.7% in the control group.There was no significant difference between two groups （χ2 =0.12, P 〈0.05 ） .Compared with the control group, the magnitude of change in FSH and LH in the treatment group and the change in the control group had no signif-icant difference （ t=0 .11 ,P〉0 .05 ） .Conclusion：The clinical efficacy of Kunbao pill has no significant difference with the efficacy of western medicine in the treatment of menopausal syndrome.Livial has no significant difference with Kun-bao pill for the improvement of the change of FSH and LH.Kunbao pill has less adverse reaction and shows certain clini-cal feasibility.
出处
《中医药学报》
CAS
2014年第5期143-145,共3页
Acta Chinese Medicine and Pharmacology
关键词
激素
更年期综合征
坤宝丸
Hormone Menopausal syndrome Chinese medicine Women
