摘要
目的：加强对利奈唑胺使用的管理,评价其处方的合理性。方法：采用回顾性研究方法,调查2012年10月-2013年2月某＂三甲＂医院所有利奈唑胺处方,从适应证、用法用量、抗菌药物管理3个方面评价。结果：110例患者中,仅28.18%的患者具有使用利奈唑胺的适应证,21.82%的患者的疗程为10-14 d,89.09%的患者每12 h 600 mg静脉滴注给药,62.73%的患者使用前接受了专家组会诊,只有35.45%的处方医师具备副高及以上职称。结论：医疗机构需要对利奈唑胺的使用进行严格管理,除遵循《抗菌药物临床应用管理办法》,加强对利奈唑胺处方权的限制措施外,还须对利奈唑胺的适应证加以控制,防止超适应证以及无适应证用药。
OBJECTIVE： To strengthen the management of linezolid use, and to evaluate the rationality of linezolid prescriptions. METHODS： By retrospective study method, all linezolid prescriptions of the hospital during Oct. 2012--Feb. 2013 were investigated and evaluated in respects of indication, usage and dosage, antibiotics management. RESULTS： Among 110 patients, only 28.18% patients suffered from indications, 21.82% received 10 to 14 days of treatment, 89.09% were given 600 mg linezolid in- travenously every 12 h and 62.73% used linezolid after experts consultations. Only 35.45% prescribers had senior professional title. CONCLUSIONS ： The application of linezolid should be managed strictly and follow Management Methods for Clinical Application of Antibiotics. The limit of right to prescribe linezolid should be strengthened, and linezolid indication must be controlled to prevent hyper-indication and no-indications use.
出处
《中国药房》
CAS
CSCD
2014年第42期3943-3945,共3页
China Pharmacy
基金
武汉大学中南医院管理基金项目(No.2013B01)
关键词
利奈唑胺
合理性
处方
Linezolid
Rationality
Prescription
