摘要
人参中主要活性成分是人参皂甙,目前发现有40多种单体,人参皂甙Rg3是研究较多的单体,对于人体各个系统如神经系统、内分泌系统、血液系统、免疫系统等均有很好的效果。近年研究发现人参皂甙Rg3具有很好的抗肿瘤作用,可抑制肿瘤新生血管形成,在肿瘤的生长、侵袭、转移过程中,起着重要作用,其作用机制与抑制血管生成因子,抑制血管内皮细胞增殖及迁移,干扰内皮细胞与细胞外基质的相互作用有关。
The main active ingredients in ginseng were ginsenosides. Ginsenosides Rg3, being the most studied monomer in the discovered 40 or more monomers,had a good effect on human-beings＇ all systems such as nervous system,endocrine sys- tem, blood system, immune system, etc. According to recent research, ginsenosides Rg3 has a good effect on ant-tumor. It can inhibit the formation of new vessels in the tumor and plays an important part in the growth, invasion and transfer of the tumor. Its mechanism of anti-tumor had a relationship with the inhibition of angiogenesis factors and proliferation and migration of vascular endothelial cell, and the interference with the interaction between endothelialcells and extracellular matrix.
出处
《长春中医药大学学报》
2014年第5期820-822,共3页
Journal of Changchun University of Chinese Medicine
基金
吉林省中医药管理局课题(2012-034)
