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瑞舒伐他汀钙对腔隙性脑梗死患者抑郁评分的影响研究 被引量:6

Rosuvastatin Calcium Tablets' Influence on Depressive Rating in Patients with lacunar cerebral infarction
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摘要 目的研究瑞舒伐他汀钙对腔隙性脑梗死患者抑郁评分的影响。方法 40例腔隙性脑梗死患者随机分为治疗组(20例)、对照组(20例),对照组给予阿司匹林、尼莫地平、血塞通、奥拉西坦等药物,治疗组在上述治疗基础上加用瑞舒伐他汀10mg qn。两组均在治疗前及治疗4周后用汉密尔顿抑郁量表对患者进行抑郁评分,并进行组间及组内比较。结果对照组治疗前后抑郁评分分别为(19.0±11.6)分、(12.9±5.5)分,比较具有统计学差异;治疗组治疗前后抑郁评分分别为(16.4±9.8)分、(8.8±4.4)分,比较具有统计学差异;两组治疗后对比有统计学差异。结论瑞舒伐他汀在常规治疗降低抑郁评分的基础上,能够进一步降低抑郁评分,改善患者生活质量。 Objective To study the Rosuvastatin Calcium Tablets’ Influence on Depressive Rating in Patients with lacunar cere-bral infarction. Methods 40 patients with lacunar cerebral infarction are randomly assigned to control group (20 patients) which is offered the medicine such as, Aspirin, Nimodipine, Xuesaitong, Oxiracetam and etc,and treatment group (20 patients) which adds10mg Rosuvastatin Calcium Tablets quaque nocte on the basis of the situation of the former group. There will be an Depres-sive rating in patients before the treatment and 4 weeks after the treatment with Hamilton's Depression Scale and a comparison of inter-group and intra-group. Results The rating scores before and after the treatment of the control group are (19.0 ±11.6) and (12.9 ±5.5)respectively with a statistical difference on comparison while the rating scores before and after the treatment of the treatment group are (16.4±9.8) and (8.8±4.4)respectively with a statistical difference on comparison. There is a statistical differ-ence existing on comparison of two groups after the treatment. Conclusion Rosuvastatin Calcium Tablets can reduce the Depres-sive rating further and improve the life’s quality of the patients on the basis of the conventional treatment of reducing the rating.
出处 《中国卫生产业》 2014年第27期23-25,共3页 China Health Industry
关键词 瑞舒伐他汀 汉密尔顿焦虑量表 腔隙性脑梗死 Rosuvastatin Calcium Tablets Hamilton's Depression Scale lacunar cerebral infarction
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