摘要
目的:探讨小骨窗显微手术时机对基底节区高血压性脑出血(HICH)疗效的影响。方法80例符合纳入标准的行小骨窗显微手术的基底节区 HICH 患者随机分为超早期组(发病6 h 内手术)和早期组(发病6~24 h 内手术),每组各40例,观察治疗疗效及患者生活质量评分变化情况。结果超早期组和早期组的再出血率分别为10.0%和15.0%,两组比较无统计学差异(P >0.05)。超早期组的手术死亡率为5.0%,明显低于早期20.0%的死亡率,比较有统计学差异(P <0.05)。术前,两组患者生活质量评分比较无统计学差异(P >0.05)。术后3个月,超早期组的生活质量评分明显高于早期组,比较有统计学差异(P <0.05)。结论超早期小骨窗显微手术可以明显降低基底节区 HICH 患者术后死亡率,并显著提高患者的生活质量,改善预后,且不增加术后再出血率,对适宜条件的患者,超早期是理想的手术时机。
Objective To investigate the effect of operation time on the curative efficacy in hypertensive intracerebral hemorrhage (HICH) in basal ganglia treating with small window craniotomy microsurgical operation. Methods 80 cases of HICH in basal ganglia treating with small window craniotomy microsurgical operation meeting the inclusion criteria were randomly divided into ultra-early group (within 6 h) and early group (6~24 h) equally. Then the curative efficacy and life quality scores were observed and compared. Results The rate of recurrent hemorrhage in the ultra-early group was 10.0%, which was statistically same with that of 15.0% in the early group (P〉0.05). Meanwhile, the ultra-early group had a mortality rate of 5.0%, which was statistically lower than that of 20.0% in the early group (P〈0.05). Before the operation, life quality scores in the two groups were statistically same (P〉0.05). Three months after, life quality scores in the ultra-early group was significantly statistically higher than that in the early group (P〈0.05). Conclusion The ultra-early small window craniotomy microsurgical operation can significant reduce mortality rate of patients with HICH in basal ganglia, improve life quality and prognosis, without increasing the rate of recurrent hemorrhage. And the ultra-early operation time is ideal for patients with optimum conditions.
出处
《中国继续医学教育》
2014年第7期29-30,共2页
China Continuing Medical Education
关键词
小骨窗显微手术
手术时间
高血压性脑出血
基底节区
Small window craniotomy microsurgical operation
Operation time
Hypertensive intracerebral hemorrhage
Basal ganglia