摘要
目的 探讨联合检测心脏型脂肪酸结合蛋白（H-FABP）、肌钙蛋白（TnI）、脑钠肽（BNP）对急性肺栓塞危险分层的评估价值.方法 选择2013年1月至2014年1月上海市奉贤区中心医院ICU及心内科确诊的急性肺栓塞患者32例,其中男性15例,女性17例.对所有患者进行危险分层,联合检测H-FABP、TnI和BNP,行血气分析、心电图、心脏彩超等检查.根据不同危险分层选择不同的治疗方法,观察不同危险分层患者的H-FABP、TnI和BNP水平,以及患者的治疗情况,分析H-FABP、TnI和BNP对急性肺栓塞危险分层的评估价值.结果 随着急性肺栓塞危险分层的增加,H-FABP、TnI和BNP水平不断升高,高危组的数值分别为（8.4±3.1）ng/ml、（0.981±0.357）ng/ml和（2458.00±1231.28）pg/ml,阳性率为100％,患者的临床过程愈加复杂,预后变差.结论 联合检测H-FABP、TnI和BNP,可用于急性肺栓塞危险分层,指导临床决策.
Objective To discuss the value of the combined detection of H-FABP, BNP and troponin to the evaluation of the risk stratification in patients of acute pulmonary embolism. Methods 32 cases of patients with acute pulmonary embolism were performed on risk stratification. All the patients were observed through combined detection of heart type fatty acid binding protein（H-FABP）, cardiac troponin I（TnI ）, BNP, blood gas analysis, electrocardiogram, and echocardiogram examination. Different treatment methods were selected according to the different risk stratification. The levels of H-FABP, TnI and BNP were evaluated in patients with different risk stratification and the conditions of treatment. The value of H-FABP, TnI and BNP in the evaluation of risk stratification in patients with acute pulmonary embolism was analyzed. Results With the increase of the risk stratification of acute pulmonary embolism, H-FABP, TnI and BNP levels rising, the value was （8.4±3.1）ng/ml, （0.981± 0.357）ng/ml, （2458.00±1231.28）pg/ml respectively, and the positive rate was 100%, and yet the patient＇s clinical process was more complex, and a worse prognosis. Conclusion H-FABP and TnI and BNP joint detection, can be used in the risk stratification of acute pulmonary embolism, and may guide the clinical decision making.
出处
《中国心血管病研究》
CAS
2014年第10期887-891,共5页
Chinese Journal of Cardiovascular Research
关键词
急性肺栓塞
心脏型脂肪酸结合蛋白
肌钙蛋白
脑钠肽
Acute pulmonary embolism
Heart type fatty acid binding protein
Cardiac troponin
Brain natriurctie peptide
