摘要
目的观察常规抗结核治疗联合异烟肼鞘内注射治疗结核性脑膜炎合并结核瘤的疗效。方法回顾性分析3例结核性脑膜炎合并结核瘤患者经常规抗结核治疗联合异烟肼鞘内注射治疗后的临床表现、CSF及影像学改变。结果本组3例患者均亚急性起病,病程中或治疗过程中合并出现结核瘤,经常规抗结核治疗联合鞘内注射治疗(异烟肼0.1 g+地塞米松5 mg),临床症状缓解,CSF恢复正常,影像学示脑部病灶消失。结论对于结核性脑膜炎合并结核瘤来说,常规抗结核治疗联合异烟肼鞘内注射治疗也许是一个有效的治疗方案。
Objective To observe the therapeutic effects of routine anti-tuberculosis therapy combined with intrathecal injection of isoniazid on treating tuberculosis meningitis combined with intracranial tuberculoma.Methods The changes of clinical symptoms,cerebrospinal fluid and MR imaging were reviewed on 3 cases of tuberculosis meningitis complicating intracranial tuberculoma.Results All of the 3 cases presented with subacute onset and intracranial tuberculoma were found in the course of disease or anti-tuberculosis therapy.By routine anti-tubercular therapy combined with intrathecal injections therapy （isoniazid 0.1 g ＋ dexamethasone 5 mg）,the clinical condition of 3 cases recovered,CSF restored to normal,and the lesions in brain were disappeared on imaging.Conclusion To tuberculosis meningitis combined with intracranial tuberculoma,routine anti-tubercular therapy combined with intrathecal injections therapy of isoniazid may be one of effective treatment options.
出处
《临床神经病学杂志》
CAS
北大核心
2014年第5期378-380,共3页
Journal of Clinical Neurology
关键词
结核性脑膜炎
结核瘤
鞘内注射
异烟肼
疗效
tuberculosis meningitis
intracranial tuberculoma
intrathecal injection
isoniazid
therapeutic effects
