摘要
目的：探讨椎管内肿瘤的诊断与手术治疗方法。方法：回顾性分析青岛大学医学院附属医院2010年1月至2013年1月施行手术治疗的246例椎管内肿瘤患者的临床资料，总结椎管内肿瘤的治疗及预后情况。结果：共施行手术262次，其中后路经双侧椎板切除入路202次，经半椎椎板切除入路28次，经椎板成形术行切除肿瘤10次，经侧方入路切除椎管外哑铃形肿瘤22次。手术后近期患者神经根性疼痛缓解率达95.0%（133/140），感觉障碍、运动障碍及括约肌功能障碍改善率分别达85.6%（125/146），86.7（136/157），84.6（11/13）。236例患者末次随访ASIA神经功能评分及分级明显优于术前及术后3个月。结论：椎管内肿瘤以良性居多，重视椎管内肿瘤的临床表现，完善体格检查，MRI是其早期诊断的首选检查方法，尽早行手术切除是提高其疗效的关键。
To investigate the diagnosis and surgical treatment of inraspinal tumors. The clinical data of 246 patients with inraspinal tumors who had undergone operations in the Affiliated Hospital of Qingdao University Medical Col ege between January 2010 and January 2013 were retrospectively analyzed. The treatment and prognosis of inraspinal tumors were reviewed. 262 operations were performed, with posterior bilateral laminectomy approach in 202 cases, semi-laminectomy approach in 28 cases, laminoplasty approach in 10 cases, and lateral resection of extra-vertebral canal dumbbel shaped tumors in 22 cases. The short-term remission rate of the nerve root pain reached 95.0%（133/140）, and the improvement rates of the sensory disability, motor disturbance, and sphincter dysfunction were 85.6%（125/146）, 86.7%（ 136/157）, and 84.6（11/13） respectively. The ASIA nervous function scores and grades at the last fol ow-up were significantly superior to those before and 3 months after the operation in 236 patients. Intraspinal tumors are mostly benign. The clinical appearance of them should be watched closely, and thorough physical check-up should be performed. MRI is the examination of choice at early diagnosis. The key to improve the treatment effects is to perform operations as soon as possible.
出处
《中国组织工程研究》
CAS
CSCD
2014年第B05期172-175,共4页
Chinese Journal of Tissue Engineering Research
关键词
椎管内肿瘤
诊断
手术治疗
intraspinal tumors
diagnosis
surgical operation
