摘要
随着后基因组时代的到来,宏蛋白质组学逐渐兴起并在生命科学基础领域和临床医药领域成功运用,宏蛋白质组学技术现已成为各研究领域炙手可热的方法之一.宏蛋白质组学技术在废水生物处理研究领域中的应用刚起步,但已展示其强大功能.本文主要综述近年来国内外宏蛋白质组学在废水生物处理研究领域的研究进展,回顾及总结了宏蛋白质组学的研究策略及应用,如鉴定功能性蛋白质/酶、揭示污染物的微生物降解途径、推断废水生物处理系统的关键代谢途径、及探讨不同污泥微生物群落微生态变化等.
With the advent of the post-genomic era, metaproteomics is gradually emerging as a new tool that has been successfully applied in life sciences and pharmacology, and has become one of the most popular methods in many research fields. Although application of metaproteomics in studying wastewater biotreatment is still in its infancy, its strong potential that contributes to basic research has already been well noticed. This paper reviewed the recent research advances in using metaproteomics to biotreatment wastewater. It also reviewed and summarized the research strategies and application of metaproteomics, such as the identification of functional proteins or enzymes, understanding of the mechanisms of pollutant biod and investigation of microbial ecosystems within egradation, deduction of key metabolic pathways, different sludge of microbial habitats.
出处
《应用生态学报》
CAS
CSCD
北大核心
2014年第10期3056-3066,共11页
Chinese Journal of Applied Ecology
基金
农业部公益性行业(农业)科研专项(201303091)
中国博士点基金新教师类项目(20120101120145)资助
关键词
宏蛋白质组学
代谢途径
降解机制
微生态
废水生物处理
metaproteomics
metabolic pathways
biodegradation mechanism
microbial ecosys-tems
biological treatment of wastewater.
