摘要
微透析技术是一种定向深入靶组织的自动生物取样技术。它可从分子水平上监测肿瘤病理生理学改变引起的靶组织药物及相关物质变化，用于评价肿瘤靶组织药物的药代动力学，优化联合用药，探究肿瘤的分子靶向治疗及进行肿瘤的早期诊断和预后，为肿瘤防治研究提供新的思路和方法。
Microdialysis is an automatic biological sampling technique that is directed into the target tissue. Microdialysis is used to monitor the changes of drug and related substances associated with pathological physiology of tumor in the target tissue at the molecular level. Microdialysis is applied to evaluate the pharmaco-kinetics of drugs in the target tissue of tumor,optimize the combination therapy,explore molecular targeted＆amp;nbsp;therapy and study the early diagnosis and prognosis of tumor. Microdialysis provides a new idea and method for the prevention and cure research of tumor.
出处
《国际肿瘤学杂志》
CAS
2014年第8期570-573,共4页
Journal of International Oncology
基金
国家自然科学基金(81301662)；中国博士后科学基金
关键词
微透析
肿瘤
药代动力学
诊断
预后
分子靶向治疗
Microdialysis
Neoplasms
Pharmacokinetics
Diagnosis
Prognosis
Molecular targeted therapy
