摘要
分析对比全麻与硬膜外麻醉对老年骨科患者术后短期认知功能的影响。将62例老年骨科患者按照抽签方法随机分为观察组和对照组各31例,对照组行全麻,观察组行硬膜外麻醉,两组均于麻醉诱导前、麻醉6h、12h、24h、72h使用简易精神状况检测(MMSE)量表评估患者认知功能。结果观察组麻醉结束6h、12h与麻醉诱导前MMSE评分比较,差异有统计学意义(P<0.05),麻醉结束24h、72h与麻醉诱导前比较,差异无统计学意义(P>0.05);对照组麻醉前与麻醉后6h、12h、24hMMSE评分比较,差异有统计学意义(P<0.05),麻醉前与麻醉后72hMMSE评分经比较,差异无统计学意义(P>0.05),说明观察组患者认知情况优于对照组(P<0.05);两组患者在麻醉前、麻醉后血压与心率比较差异无统计学意义(P>0.05)。硬膜外麻醉对老年骨科患者术后短期认知功能的不良影响明显小于全身麻醉。
To study the influence of general anesthesia and epidural anesthesia on postoperative short-term cognitive function in the elderly patients undergoing orthopedics surgery. A total of 62 cases of elderly orthopedic patients according to balloting were randomly divided into observation group and control group with 31 cases each group. Control group underwent general anesthesia,observation group underwent epidural anesthesia. Cognitive function was detected by MMSE before induction of anesthesia and 6h, 12h,24h and 72h after anesthesia. The scores of MMSE in observation group at 6h and 12h were lower （P〈0.05）, while there was no difference at 24h and 72h （P〈0.05）as compared with pre-induction of anesthesia. The scores of MMSE in control group at 6h, 12h and 24h were decreased as compared with pre-induction of anesthesia （P〈0.05）, while no difference was found at 72h （P〉0.05）. There were no differences in BP and heart rate during operation between the two groups （P〉0.05）. Compared with general anesthesia, epidural anesthetic has less impact on short-term cognitive function,which can reduce the incidence of postoperative cognitive dysfunction in elderly patients.
出处
《医学与哲学（B）》
2014年第9期26-27,共2页
Medicine & Philosophy(B)
关键词
全身麻醉
硬膜外麻醉
认知功能
general anesthesia, epidural anesthesia, cognitive function
