摘要
目的:观察参芪扶正注射液对晚期非小细胞肺癌(NSCLC)患者化疗期间不良反应的影响。方法:102例经病理学确诊为NSCLC患者随机分为观察组50例和对照组52例。观察组行参芪扶正注射液联合GP方案化疗,对照组行GP方案化疗,3周为一周期,至少2个周期后比较两组不良反应发生情况。结果:观察组血液学毒性、胃肠道反应发生率低于对照组,观察组生活质量较对照组有较大改善。结论:参芪扶正注射液具有一定降低NSCLC患者化疗相关不良反应发生的作用,并可适当改善患者生活质量。
Objective：To observe the efficacy of Shenqi Fuzheng（SF）injection,a traditional Chinese medicine,in the treatment for adverse reactions during chemotherapy in patients with advanced non-small cell lung cancer（NSCLC）.Methods：A total of 102 patients with pathologically confirmed NSCLC were randomly divided into SFinjection group（n=50）and control group（n=52）.SFinjection group were treated with SFinjection combined with chemotherapy with GP regimen,while the control group were only received GP chemotherapy.One treatment cycle contains three weeks,and the occurrence of adverse reactions were compared after two cycles at least.Results：The hematological toxicity and gastrointestinal reaction rates were lower than those in the control group,and the quality of life of SFinjection group were also greatly improved when compared with control group.Conclusion：SFinjection could reduce the occurrence of chemotherapy-related adverse reactions in patients with NSCLC,and could improve the quality of life in NSCLC patients.
出处
《武汉大学学报（医学版）》
CAS
北大核心
2014年第5期744-746,共3页
Medical Journal of Wuhan University
关键词
非小细胞肺癌
参芪扶正注射液
不良反应
Non-Small Cell Lung Cancer Shenqi FuzhengInjection Adverse Reactions
