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中国成年人体重指数与心血管危险因素关系的研究 被引量:41

Study on the relationship between BMI and the risk of cardiovascular among Chinese adults
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摘要 目的 探讨中国成年人BMI与主要心血管危险因素及其聚集的关系.方法 2010年在全国31个省(区、市)的162个监测点,采用多阶段分层整群随机抽样方法,调查了98 271名>18岁居民.采用面对面询问调查、身体测量和实验室检测方法收集吸烟、饮酒、膳食、身体活动等慢性病主要危险因素及高血压、糖尿病、血脂异常等主要慢性病患病情况.将24 kg/m2≤BMI<28 kg/m2和≥28 kg/m2定义为超重和肥胖,在对样本经过复杂加权后,分析不同BMI组别人群心血管危险因素及其聚集情况.结果 我国成年人超重率和肥胖率分别为30.6% (95%CI:29.5%~31.7%)和12.0%(95%CI:11.0%~12.9%),男性超重率高于女性,差异有统计学意义(x2=16.09,P<0.001),45 ~ 65岁组人群超重率和肥胖率最高(x2值分别为485.17和112.23,P<0.001).心血管危险因素(SBP、DBP、TG、TC、HDL-C、LDL-C、FPG和空腹胰岛素水平)均随着BMI的增加而增加,超重和肥胖组均高于正常组,差异有统计学意义(超重组:F值分别为4 056.19、6 860.70、3 898.91、1 624.73、2 337.21、2 558.01、1 049.01和1 665.52,P<0.001;肥胖组:F值分别为5 628.68、9 949.81、5 508.77、1 656.34、2 452.05、2 365.92、1 441.72和6 081.27,P<0.001).高血压、血脂异常、糖尿病、胰岛素抵抗和心血管危险因素聚集的患病率均随着BMI的增加而增加,超重和肥胖组均高于正常组,差异有统计学意义(超重组:x2值分别为704.70、521.86、431.35、449.13和686.83,P<0.001;肥胖组:x2值分别为113.45、645.03、1 063.30、1 547.86和1 909.66,P<0.001).多因素分析显示,调整年龄和性别后,超重和肥胖组高血压、血脂异常、糖尿病、胰岛素抵抗和心血管危险因素聚集的发病风险分别为正常组的2.5和5.5、2.2和3.4、1.8和2.9、2.9和8.2、3.3和8.9倍.结论 我国成年人随着BMI的增加,患心血管疾病的危险增大,应将控制BMI作为� Objective To study the relationship between body mass index (BMI) and cardiovascular risk factors among Chinese adult population.Methods 98 271 subjects aged 18 years or over were recruited from 162 surveillance points around 31 provinces in China' s mainland in 2010,under a complex multistage stratified sampling method.The survey included face-to-face interview,physical measurement and laboratory testing,to collect information related to the prevalence of risk factors as smoking,drinking,diet and physical activities as well as the prevalence of main chronic disease as hypertension,diabetes and dyslipidemia.24 kg/m2≤BMI〈28 kg/m2 was defined as overweight and BMI≥28 kg/m2 was defined as obese.After a complex weighting on the sample,level and proportion of cardiovascular risk factors in groups of different BMI were analyzed.Results The overall prevalence rates of overweight and obesity were 30.6% (95%CI:29.5%-31.7%) and 12.0%(95%CI:11.0%-12.9%) and were significantly higher in men for overweight (x2=16.09,P〈0.001) and those aged 45-65 years old for both overweight and obesity (x2 values were 485.17 and 112.23 both P〈0.001),respectively.The levels of systolic blood pressure (SBP),diastolic blood pressure (DBP),triglyceride (TG),total cholesterol (TC),high density lipoprotein-cholesterol (HDL-C),low density lipoprotein-cholesterol (LDL-C),fasting plasma glucose (FPG) and fasting blood insulin (FBI) showed a significantly increase on BMI and were seen higher in overweight (F values were 4 056.19,6 860.70,3 898.91,1 624.73,2 337.21,2 558.01,1 049.01 and 1 665.52,with both Ps〈0.001) respectively and obese participants (F values were 5 628.68,9 949.81,5 508.77,1 656.34,2 452.05,2 365.92,1 441.72 and 6 081.27,respectively; all Ps〈0.001).The prevalence rates of hypertension,dyslipidemia,diabetes,insulin resistance and clustering of cardiovascular disease showed a significantly increase on BMI and were higher in overweight (x2 values were 704.
出处 《中华流行病学杂志》 CAS CSCD 北大核心 2014年第9期977-980,共4页 Chinese Journal of Epidemiology
基金 感谢原卫生部疾病预防控制局、中国疾病预防控制中心、中国31个省、自治区、直辖市和新疆生产建设兵团卫生行政部门和疾病预防控制中心给予本次调查的支持 感谢国家项目专家组和工作组,31个省、自治区、直辖市及新疆生产建设兵团项目工作组和162个监测点项目工作组的所有调查队员所付出的努力 感谢所有调查对象的配合与支持
关键词 体重指数 超重 肥胖 心血管危险因素 Body mass index Overweight Obesity Cardiovascular risk factors
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