摘要
目的观察用右归丸加减联合食疗干预治疗肾阳不足型围绝经期水肿的临床疗效。方法将73例中医辨证诊断为肾阳不足型围绝经期水肿患者随机分为两组。对照组给予利尿药氢氯噻嗪治疗,治疗组给予右归丸加减,并给予合理的饮食指导和干预,两组均以15d为1个疗程,2个疗程结束后对两组临床疗效、症状改善情况等进行比较。结果治疗结束后,治疗组的总有效率明显高于对照组(P<0.05);治疗组的浮肿、畏寒肢冷、体重、食欲、尿量等症状改善的程度明显优于对照组(P<0.05);治疗组24h尿蛋白、血肌酐水平较治疗前和对照组有明显下降,血浆白蛋白则有明显上升(P<0.05);治疗组不良反应发生率明显少于对照组(P<0.05)。结论右归丸配合饮食干预治疗肾阳不足型围绝经期水肿,能有效改善患者的临床症状,促进水肿的消退,且副作用少。
Objective To investigate the clinical efficace of Youguiwan decoction and diet intervention in treatment of perimenopansal edema. Methods 73 cases of kidney yang - deficiency type of edema were randomly divided into two groups. The control group were treated with bydrochlorothiazide, while treatment group were treated with Youguiwan decoction and diet intervention for treatment, 15 days as a course. After two courses of treatment, the clinical efficacy,clinical symptoms improvement between two groups was compared. Results The total effective rate of treatment group was significantly higher lhan control group（ P 〈 0.05 ） ;the clinical symptoms improvement such as edema, chilly, cold limbs, weight, appetite and urine output in treatment group were better than control group （P 〈 0.05 ） ;the laboratory index of 24h urinary protein content and the level of serum creatinine ：n treatment group was significantly lower than that of control group, while the level of plasma albumin was obviously higher than that of the control group（ P 〈 0.05 ） ; the adverse reaction in treatment group was significantly lower than control group （ P 〈 0.05 ）. Conclusion Youguiwan decoction combined with diet intervention in treatment of perimenopausal edema can improve the clinical symptoms, promote the edema subsided and has less side effects, is worthy of further research and development.
出处
《湖北中医药大学学报》
2014年第4期31-33,共3页
Journal of Hubei University of Chinese Medicine
关键词
围绝经期水肿
肾阳不足型
中医药疗法
食疗
perimenopansal edema
kidney yang - deficiency
TCM therapy
diet intervention
