摘要
目的:观察中药复方益气消征方(YQXZF)与5-氟尿嘧啶(5-fu)对体外培养人胃癌(SGC-7901)细胞、人乳腺癌(Bcap-37)细胞、人宫颈癌(Hela)细胞、人前列腺癌(PC-3)细胞、人肺癌(A549)细胞增殖作用的影响。方法:采用MTT比色法测定各种细胞增殖作用的比较,取不同浓度益气消征方和5-氟尿嘧啶,分别体外作用于SGC-7901、Bcap-37、Hela、PC-3、A549细胞。结果:益气消征方对SGC-7901、Bcap-37、Hela、PC-3、A549细胞有不同程度的抑制作用,其抑制作用具有剂量效应关系。结论:中药复方益气消征方具有抑制体外SGC-7901、Bcap-37、Hela、PC-3和A549细胞增殖的作用。
Objective:To observe the proliferation condition of Chinese medicine Formula of Replenishing Qi and Eliminating Signs (YQXZF)and 5-fluorouracil (5-fu)effect on human gastric cancer SGC-7901 ceils, human breast cancer ( Bcap-37 ) cells, human cervical cancer ( Hela ) cells, human prostate cancer PC-3 ceils, human lung cancer ( A549 ) cells. Methods: The cell proliferation inhibition rate was detected by MTT assay. Results:The Chinese medicinal YQXZF has different degrees of inhibition on tumor ceils. Conclusion : The Chinese medicinal YQXZF can inhibit the proliferation of Bcap-37, SGC-7901, PC-3, Hela, A549 tumor cells in vitro.
出处
《辽宁中医药大学学报》
CAS
2014年第9期26-28,共3页
Journal of Liaoning University of Traditional Chinese Medicine
基金
大连市科学技术局项目(2013E15SF143)
关键词
中药复方益气消征方
5-氟尿嘧啶
抑制肿瘤细胞增殖
Chinese medicine Formula of Replenishing Qi and Eliminating Signs ( YQXZF )
5-fluorourac
tumor cell inhibition