摘要
目的观察2型糖尿病患者不同病程阶段经颅多普勒超声(transcranial Dopplersonograghy,TCD)变化,探讨糖尿病病程与脑血管病变的关系。方法选择2型糖尿病患者80例,根据病程分为2组,A组(病程≥10年)40例,B组(病程<10年)40例,并选择健康体检者40例作为对照组(C组)。行TCD检查,比较3组左右两侧大脑中动脉(middle cerebral artery,MCA)及左右两侧椎动脉(vertebral artery,VA)的收缩期峰值血流速度及搏动指数(pulseindex,PI)。结果 A组和B组左右两侧MCA及左右两侧VA的收缩期峰值血流速度明显高于C组(P<0.01),A组左右两侧MCA及左右两侧VA的收缩期峰值血流速度明显高于B组(P<0.01);A组左右两侧MCA及左右两侧VA的PI值明显高于B组和C组(P<0.01),B组左右两侧MCA及左右两侧VA的PI值与C组比较差异无统计学意义(P>0.05)。结论糖尿病患者脑血管病变与糖尿病病程具有一定的关系,TCD检查提供了脑血管功能状态的重要信息。
Objective To explore the relationship between duration of diabetes mellitus and cerebrovascular disease by observing the variation of transcranial Doppler sonograghy（TCD）in different stages of type 2 diabetes mellitus patients. Methods Eighty type 2 diabetes mellitus patients who were hospitalized or confirmed in the department of our hospital were divided to two groups,40 patients in group A（disease course≥10 years）and 40 patients in group B（disease course ﹤ 10 years）. The group C including 40 health persons with similar age served as control group（ group C）. The systolic peak velocity（VP）and pulsatility index（PI）of middle cerebral artery（MCA）of left and right sides and vertebral artery（VA）of left and right sides in three groups were detected by TCD. Results The VP of MCA of left and right sides and VA of left and right sides of group A and group B were significantly higher than those of group C（P ﹤ 0. 01）,the VP of MCA of left and right sides and VA of left and right sides of group A were much higher than those of group B（P ﹤ 0. 01）,the PI of MCA of left and right sides and VA of left and right sides of group A were much higher than those of group B and group C（P ﹤ 0. 01）, and there were no significant statistic differences between the PI of MCA of left and right side and VA of left and right side of group B and group C（P ﹥ 0. 05）. Conclusion The cerebrovascular disease may be related to disease course of diabetes mellitus patients and TCD test can provide important information in functional status of cerebral blood vessels.
出处
《河北医科大学学报》
CAS
2014年第8期901-903,共3页
Journal of Hebei Medical University
关键词
糖尿病
2型
脑血管损伤
超声检查
多普勒
diabetes mellitus, type 2
cerebrovascular trauma
ultrasonography, Doppler
