摘要
目的探讨MR扩散张量成像(DTI)技术定位及定量评价腰骶神经根压迫症的临床应用价值。方法临床专科检查诊断为单侧L5神经支配区域神经根压迫症患者50例,行常规MRI及DTI检查,定量测量L5神经根各向异性分数(FA)值,同时进行双侧L3至S1神经根神经纤维束扩散张量纤维束成像(DTT)。相同层面健患侧神经根FA值及神经根远近端FA值比较采用配对t检验法。结果 (1)椎间孔内侧感兴趣区(ROI)L5神经根近端FA值:患侧为0.206±0.031,健侧为0.232±0.029,患侧L5神经根近端FA值低于健侧,差异有统计学意义(t=4.668,P<0.01)。(2)椎间孔外侧ROI L5神经根远端FA值:患侧为0.152±0.026,健侧为0.229±0.023,患侧L5神经根远端FA值低于健侧,差异有统计学意义(t=17.854,P<0.01)。(3)患侧L5神经根远端FA值低于近端,差异有统计学意义(t=10.139,P<0.01)。(4)健侧L5神经根远近端FA值差异无统计学意义(t=0.673,P=0.504>0.01)。(5)DTT腰骶丛神经纤维束示踪成像,47例患侧L5神经根神经纤维束出现节段性稀疏、变窄、截断等现象,3例患侧L5神经根神经纤维束形态及走行与健侧大体一致。结论 DTI结合常规MRI对定位诊断腰骶神经根压迫症及定量评价病变神经根有一定的临床意义。
Objective To discuss the clinical application of diffusion tensor imaging （DTI） in quantitatively evaluating lumbosacral nerve root compression syndrome. Methods Fifty patients with clinically-proved unilateral lumbar nerve root compression syndrome due to foraminal stenosis were enrolled in this study. Routine MRI and DTI were performed, and FA values of L5 nerve root were measured. Meanwhile, diffusion tensor tractography （DTF） of bilateral L3 - S1 nerve roots was also carried out. The FA values of healthy side nerve root were compared with those of diseased side nerve root at the same levels using paired-samples t test. Results （ 1 ） On the proximal side of L5 nerve roots, the mean FA values of diseased and healthy side were 0. 206 ± 0.031 and 0. 232±0. 029 respectively. The difference between the two sides was statistically significant （t =4. 668, P 〈 0.01 ）. （2） On the distal side of L5 nerve roots, the mean FA values of diseased and healthy side were O. 152±0. 026 and 0. 229±0. 023 respectively, The difference between the two sides was statistically significant （ t = 17. 854, P 〈 0.01 ）. （3） The mean FA values of L5 distal nerve root on the diseased side were significantly lower than that of L5 proximal nerve root （t = 10. 139, P 〈0.01 ）. （4） On the healthy side, the differences in L5 nerve root FA values between proximal and distal part were not significant （ t = 0. 673, P = 0. 504 ）. （ 5 ） DTI＇ of lumbosacral nerve plexus showed that tract disruption, narrowing and abrupt break of L~ nerve root were displayed in 47 cases. Conclusion Combination use of routine MRI and DTI is helpful in quantitatively evaluating lumbosacral nerve root compression syndrome.
出处
《临床放射学杂志》
CSCD
北大核心
2014年第8期1229-1232,共4页
Journal of Clinical Radiology
关键词
磁共振成像
扩散张量成像
腰骶丛神经根病
Magnetic resonance imaging Diffusion tensor imaging Lumbosacral plexus nerve compression syndromes
