摘要
目的探讨影响老年卵巢癌患者复发的危险因素。方法分析经病理组织学确诊的137例老年卵巢癌患者的临床资料，其中复发33例。对可能影响复发的8个因素包括肿瘤分期、病理类型、组织分级、术中是否清扫淋巴结、化疗方案、化疗周期、初次治疗后无瘤生存时间和术后是否有肉眼可见残瘤进行单因素分析及多元logistic回归分析，探讨老年卵巢癌患者复发的影响因素。结果单因素分析及多元logistic回归分析均显示肿瘤分期（OR=3．463，95％CI=l_167～10．276）、组织分级（OR=4．627，95％CI=1．367～15．66）和有肉眼可见残瘤（OR=6．679，95％CJ=1．700～26．235）对老年卵巢癌患者的复发有显著影响。结论肿瘤分期、组织类型、有肉眼可见残瘤是老年卵巢癌患者复发的重要影响因素。
Objective To explore the impact of risk factors of the recurrence of senile patients with ovarian cancer. Methods A retrospective analysis of 137 cases of ovarian cancer in elderly patients. The recurrence in 33 cases and non- recurrence in 104 cases were taken. The factor that might influence the recurrence, including tumor stage, pathological type, histological type, intraoperative lymph node dissection, chemotherapy, chemotherapy cycle, after initial treatment, tumor free survival time and postoperative macroscopic residual tumor, were studied by single factor analysis and multivariate logistic regression analysis to find out the influence factors for the recurrence of senile patients with ovarian cancer. Results Single factor analysis and multivariate logistic regression analysis showed that tumor stage （OR=3. 463, 95%Cl=1.167～10.276）; tissue type （OR= 4. 627, 95%Cl=1. 367～15. 66） and macroscopic residual tumor （OR= 6. 679, 95%C1=1. 700～26. 235） had a significant impact on elderly patients with recurrent ovarian cancer. Conclusion Tumor stage, histological type, macroscopic residual tumor were the factors that affect the recurrence of elderly patients with ovarian cancer.
出处
《西部医学》
2014年第9期1167-1169,共3页
Medical Journal of West China
关键词
卵巢癌
老年
预后影响因素
Ovarian cancer Aged
prognostic factors
