摘要
目的探讨甲基强的松龙鞘内注射治疗多发性硬化病患者的临床效果。方法对我院接收治疗的40例多发性硬化病患者资料进行分析,将患者根据入院时间顺序随机分为两组。对照组采用红花、依达拉奉,甲钴胺同时配合中药治疗,实验组在对照组基础上联合甲基强的松龙鞘内注射治疗,比较两组治疗效果。结果实验组治疗总有效率为90%,与对照组相比,差异有统计学意义(65%)(P<0.05);实验组在我院治疗后对我院总体满意度较高,达到90%,高于对照组(P<0.05);实验组临床症状评分为(18.80±3.45)、神经功能体征评分为(9.11±2.40)、EDSS评分为(6.43±1.71),与对照组相比,差异有统计学意义(P<0.05);实验组治疗后在我院住院(2.6±0.4)d,短于对照组(P<0.05)。结论红花、依达拉奉,甲钴胺同时配合中药治疗基础上采用甲基强的松龙鞘内注射治疗多发性硬化病效果显著,值得推广使用。
Objective To investigate the clinical effect of intrathecal injection of methylprednisolone for the treatment of multiple sclerosis patients. Methods Our hospital receiving treatment of 40 cases of multiple sclerosis were analyzed,the patients were randomly divided into two groups of time.The control group using safflower,edaravone,mecobalamin and combined with traditional Chinese medicine therapy,the experimental group in the control group based on the combined with intrathecal injection of methylprednisolone treatment,treatment effects were compared between the two groups. Results In the experimental group, the total effective rate was 90%and the control group compared with the significant advantage（65%）（P〈0.05）;the experiment group were higher in our hospital overall satisfaction in our hospital after treatment,up to 90%higher than that of the control group（P〈0.05）;clinical symptoms in experimental group was（18.80±3.45）,nerve function symptoms score（9.11±2.40）, EDSS score（6.43±1.71） and compared with the control group,a significant advantage（P〈0.05）;the experiment group after treatment in our hospital（2.6±0.4） shorter than the control group（P 〈 0.05）. Conclusion Edaravone and Mecobalamin,safflower,at the same time with Chinese medicine treatment based on the use of intrathecal injection of methylprednisolone for the treatment of multiple sclerosis disease effect,is worthy to be popularized.
出处
《中国医药科学》
2014年第15期39-41,共3页
China Medicine And Pharmacy
