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2008年-2011年漯河市麻疹和风疹疑似病例血清学检测分析 被引量:6

Analysis of serological detection results of suspected measles and rubella cases in Luohe city from 2008 to 2011
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摘要 目的了解漯河市麻疹和风疹的流行情况,为防治麻疹、风疹提供科学依据。方法采用酶联免疫(ELISA)方法对漯河市疑似病例血清麻疹、风疹IgM抗体进行检测。结果 2008年-2011年漯河市共检测290份疑似病例血清样本,麻疹IgM抗体阳性169份,总阳性率58.28%;风疹IgM抗体阳性31份,总阳性率10.69%。各年度麻疹、风疹阳性率差异有统计学意义,呈下降趋势。性别分布差异无统计学意义,男女感染发病无差别。年龄分布,麻疹主要分布在1岁~10岁,占IgM抗体阳性总例数的82.94%,风疹主要分布在1岁~20岁,占IgM抗体阳性总例数的90.32%。结论4年来漯河市麻疹发病有下降趋势,为达到消除麻疹的目标,在加强常规免疫外,应重点加强对托幼机构、中小学校及外来人员聚集处加强监督管理,避免麻疹、风疹暴发流行。 LIU Jun-hua;WANG Guang-yang;ZHAO Wen-li;REN Yun-hui;Luohe Center for Disease Prevention and Control; Objective To study the epidemic situation of measles and rubella in Luohe city,so as to provide scientific basis for prevention and control of measles and rubella. Methods IgM antibody was detected in suspected measles and rubella cases by ELISA in Luohe city. Results From 2008 to 2011,290 serum specimens from suspected measles and rubella cases were determined in Luohe,the total measles IgM positive rate was 58. 28%(169/290),while the rubella IgM positive rate was 10. 69%(31/290). The positive rates of measles and rubella decreased year by year,and the difference had statistical significance.There was no statistical difference between males and females in positive rate of measles and rubella. In terms of age distribution,measles IgM positive rate was the highest between 1 and 10 years old(82. 94%),while the rubella IgM positive rate was the highest between 1 and 20 years old(90. 32%). Conclusion In recent four years,the incidence rate of measles markedly reduced in Luohe city. It is highly required that the routine immunization should be strengthened,especially the supervision and management on nurseries and kindergartens,primary and middle schools,as well as floating population areas,thus avoiding the outbreak of measles and rubella.
出处 《中国卫生检验杂志》 北大核心 2014年第15期2245-2247,共3页 Chinese Journal of Health Laboratory Technology
关键词 麻疹 风疹 IGM抗体 Measles Rubella IgM antibody
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