摘要
目的对比分析无水乙醇与聚桂醇注射液治疗单纯性肾囊肿的临床疗效与安全性。方法 A组：2008年2月-2010年3月收治的81例（共85个囊肿）单纯性肾囊肿患者注射无水乙醇;B组：2010年4月-2012年5月收治的87例（共94个囊肿）单纯性肾囊肿患者注射聚桂醇注射液。两组均在超声引导经皮囊内注射,对比观察两组患者的不良反应及疗效。结果治疗后A组患侧腰部不适发生率显著高于B组,差异有统计学意义（P〈0.05）;A组穿刺治疗中针道出血发生率显著高于B组,差异有统计学意义（P〈0.05）;A组穿刺治疗中囊内出血发生率低于B组,差异无统计学意义（P〉0.05）。两组均随访12月以上,A组治愈率高于B组,差异无统计学意义（P〉0.05）。两组均未出现肾脏损伤、感染等严重并发症。结论聚桂醇注射液治疗单纯性肾囊肿的疗效与无水乙醇相同,但不良反应明显少于后者,更为安全有效。
Objective To investigate the clinical effects and safety of absolute alcohol injection and lauromacrogol injection for sclerotherapy of pure renal cysts by Ultrasound-guided.Methods Group A：from February 2008 to March 2010,85 lesions in 81 cases of pure renal cysts with absolute alcohol injection;Group B：From April 2010 to May 2012,94 lesions in 87 cases of pure renal cysts with lauromacrogol injection.The two group injections were guided by Ultrasound.We observed and compared the adverse effects and effective rates of the two groups.Results The occurrence rate of waist discomfort in group A was 33.3%,and it was 11.5%in group B,the difference between the two groups was statistically significant（P〈0.05）.The occurrence rate of intracystic hemorrhage in group A was 4.7%,and it was 5.3% in group B,there was no statistically significant difference between the two groups（P〈0.05）.We followed up for 12 months or more,the cure rate was 90.6%in A group while it was 88.3%in group B,and there was no statistically significant difference between the two groups（P〈0.05）.No serious complications such as recurrent laryngeal nerve injury and infection occurred in both groups.Conclusion The clinical effects of lauromacrogol injection and absolute alcohol injection in treatment for pure renal cysts are similar,but lauromacrogol injection is safer than absolute alcohol.
出处
《成都医学院学报》
CAS
2014年第4期439-442,共4页
Journal of Chengdu Medical College
基金
中国高校医学期刊临床专项资金(NO:11321426)
关键词
聚桂醇注射液
无水乙醇
超声引导
单纯性肾囊肿
硬化治疗
Lauromacrogol Injection Absolute Alcohol Ultrasound-Guided Pure Renal Cysts Sclerotherapy
