摘要
目的:探讨多囊卵巢综合征(PCOS)患者血浆内脂素水平的变化及其临床意义。方法:回顾性分析88例PCOS患者(观察组)及60例健康妇女(对照组)的体重指数(BMI)、血浆内脂素以及腰臀比等资料,根据BMI将两组再次分为肥胖组与非肥胖组,并在各组之间进行对比分析,同时分析PCOS患者血浆内脂素与BMI、腰臀比的相关性。结果:观察组患者肥胖率(78.4%)显著高于对照组(25.0%)(P<0.01);观察组BMI、血浆内脂素水平以及腰臀比均显著高于对照组(P<0.01);观察组内两组患者血浆内脂素水平均显著高于对照组内两组(P<0.01);PCOS患者血浆内脂素水平与BMI、腰臀比均呈显著正相关(P<0.05)。结论:PCOS患者血浆内脂素水平显著增高,且与BMI及腰臀比密切相关,可作为PCOS的一种新型实验室指标进行辅助诊断。
To discuss the changes and significance of visfatin in patients with PCOS .Meth-od：88 patients with PCOS （ the observation group ） and 60 healthy women （ the control group ） were retro-spectively analyzed , the observation group and control group were divided into the observation obese group , observation non-obese group , control obese group , control non-obese group again according to BMI , then the BMI, plasma visfatin, and waist hip ratio（WHR） were contrasted between the groups , and the relation-ship of plasma visfatin with BMI and WHR were analyzed .Result：Obesity rate in the observation group （ 78. 4%） was significantly higher than the control group （25.0%）（ P〈0.01）; BMI, plasma visfatin, and WHR in the observation group were significantly higher than the control group （P〈0.01）;plasma visfatin in the two subgroup of the observation group was significantly higher than those in control group （ P〈0.01）; and there was a significant positive correlation between plasma visfatin BMI and WHR （P〈0.05）.Conclusion：Plasma visfatin levels were significantly increased in patients with PCOS , and closely related with BMI and WHR .So plasma visfatin can use as a new laboratory parameters in PCOS diagnosis .
出处
《河北医学》
CAS
2014年第11期1791-1793,共3页
Hebei Medicine
基金
广东省深圳市2011年科技计划资助项目
(编号:20110217)
关键词
内脂素
多囊卵巢综合征
血浆
Visfatin Polycystic ovarian syndrome Serum
