摘要
目的探讨新疆地区泌尿系统结石的主要危险因素,为泌尿系统结石防治提供依据;方法采用病例对照研究方法,选取2010年1月—2013年12月在新疆医科大学第五附属医院确诊的泌尿系统结石患者176例患者为病例组,并选取同期在医院体检正常的176名健康人群为对照组,采用问卷调查各组研究对象的人口学特征、饮水饮食情况等,并检测相关实验室指标。结果高盐饮食(OR=7.571)、高脂饮食(OR=2.269)、有泌尿系统结石病家族史(OR=3.584)、长期服用药物(OR=4.755)、尿酸水平高(OR=2.485)、尿液酸性下降(OR=4.054)是患泌尿系统结石的危险因素(均P<0.05),日饮水量多(OR=0.215)是患泌尿系统结石的保护性因素(P<0.05)。结论泌尿系统结石病的预防和控制应避免盐和脂肪的多余摄入,增加饮水量,有家族遗传史及>50岁人群应加强关注。
Objective To explore risk factors of urinary system calculi and to provide evidences for developing control measures for the disease. Methods A case-control study was conducted among 185 newly diagnosed urinary system calculi patients and 360 healthy physical examinees without urinary system calculi in Fifth Affiliated Hospital of Xinjiang Medical University from 2010 to 2013. The participants of the study were interviewed face-to-face with a questionnaire about demographic characteristics, dietary behavior, drinking water, and family history of genetic diseases and blood lip- ids, uric acid,pH of urine and urinary tract infections of the participants were also detected. Results The results of mult- ivariate logistic regression showed that the risk factors of urinary system calculi included aged ≥ 50 years （ odds ratio [ OR] = 3. 335 ）, salty diet（ OR = 7. 571 ）, high-fat diet （ OR = 2. 269 ）, familial history of urinary system calculi （ OR = 3.584 ）, long-term medication （ OR = 4. 755 ）, high uric acid （ OR = 2. 485 ）, and increased urine pH （ OR = 4. 054 ） （ all P 〈 0. 05）, while drinking a large amount of water daily was a protective factor （ P 〈 0. 05 ）. Conclusion Decreasing salty and high-fat diet and increasing daily amount of drinking water may be helpful to the prevention of urinary system calculi, especially among the people aged 50 years and older and those with familial history of urinary system calculi.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2014年第9期1202-1204,共3页
Chinese Journal of Public Health
关键词
泌尿系统
结石
危险因素
urinary system
calculi
risk factor
