摘要
目的观察纳洛酮治疗慢性阻塞性肺疾病并Ⅱ型呼吸衰竭的临床效果。方法选取本院呼吸内科收治的明确诊断为慢性阻塞性肺疾病并Ⅱ型呼吸衰竭的患者78例,将其随机分为治疗组和对照组各39例。两组均给予常规治疗,对照组在常规治疗的基础上加尼可刹米,治疗组在常规治疗的基础上加纳洛酮,比较两组的治疗效果及血气分析结果。结果治疗组总有效率(87.18%)明显高于对照组(64.10%),差异有统计学意义(P<0.05)。治疗组血气指标的改善情况明显优于对照组,差异有统计学意义(P<0.05)。结论纳洛酮治疗慢性阻塞性肺疾病并Ⅱ型呼吸衰竭,效果显著,安全有效,值得临床广泛应用。
Objective To investigate the clinical effect of naloxone in the treatment of chronic obstructive pulmonary disease （COPD） with typeⅡrespiratory failure. Methods 78 cases of patients with COPD and type Ⅱ respiratory failure were randomly divided into treatment group and control group,39 cases in each group.Patients in two groups were both given with routine treatment,while patients in control group were added with nikethamide and patients in treatment group were added with naloxone.The therapeutic effect and the results of blood gas analysis were compared. Results The total effective rate in treatment group （87.18%） was higher than that in control group （64.10%）,the difference was significant （P〈0.05）.The improvement of results of blood gas in treatment group was more than that in control group,the difference was significant （P〈0.05）. Conclusion Naloxone can improve the clinical effect of the treatment of COPD with type Ⅱ respiratory failure,it is safe and can be used in clinic widely.
出处
《中国当代医药》
2014年第23期70-71,共2页
China Modern Medicine
关键词
纳洛酮
慢性阻塞性肺疾病
Ⅱ型呼吸衰竭
Naloxone
Chronic obstructive pulmonary disease
Type II respiratory failure
